フルプレドニソロン

MSDS Information

• 6a-Fluoroprednisolone

フルプレドニソロン 化学特性,用途語,生産方法

• 効能

  抗炎症薬, グルココルチコイド受容体作動薬

• 説明

  Fluprednisolone (6α-fluoro-11β,17,21-trihydroxy-pregna-1,4-diene-3,20-dione) is the 16-desmethyl analogue of paramethasone. Its activity is similar to that of paramethasone, and it has approximately 2.5 times the antirheumatic potency of prednisolone. With doses of 2 to 7 mg, evidence of salt and water retention has not been noted. The therapeutic index, however, probably is the same or only a little greater than that for prednisolone. Because no new adverse reactions have been noted during the administration of this drug on a short-term basis, it seems that a 6α-fluoro group does not deleteriously affect the activity of prednisolone (49,75).

• 使用

  6α-Fluprednisolone is an anti-inflammatory corticosteroid metabolite.

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