モエキシプリル塩酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H400：水生生物に強い毒性

• 注意書き

  P273：環境への放出を避けること。

  P391：漏出物を回収すること。

  P501：内容物/容器を．．．に廃棄すること。

モエキシプリル塩酸塩 価格

モエキシプリル塩酸塩 化学特性,用途語,生産方法

• 効能

  血圧降下薬, アンジオテンシン変換酵素(ACE)阻害薬

• 説明

  Moexipril hydrochloride is a novel ACE inhibitor first marketed in the U.S.A. for the treatment of hypertension as a monotherapy and as a second-line therapy in combination with diuretics or calcium antagonists. Like other ACE inhibitors, moexipril is a prodrug that is converted in the liver to its diacid moexiprilat which is the active agent. Moexipril displays a higher in vitro inhibitory potency to ACE than enalapril although its effectiveness in reduction of blood pressure in hypertensive patients is similar to that seen with enalapril. It is orally active with a rapid onset and prolonged duration of action. Excellent tolerability has been reported. Moexipril is distinguished by its lower cost than other marketed ACE inhibitors.

• 化学的特性

  Crystalline Solid

• 使用

  Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril

• 危険性

  Moderately toxic by ingestion.

• 生物活性

  Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC 50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.

モエキシプリル塩酸塩 上流と下流の製品情報

モエキシプリル塩酸塩 生産企業

Global(144)Suppliers

モエキシプリル塩酸塩 スペクトルデータ(¹HNMR)

82586-52-5, モエキシプリル塩酸塩 キーワード