2-(ホスホノオキシ)プロペン酸/カリウム,(1:1)

化学名:2-(ホスホノオキシ)プロペン酸/カリウム,(1:1)

CAS番号.4265-07-0

英語名:PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT

CBNumberCB5778797

MFC3H4KO6P

MW206.13

MOL File4265-07-0.mol

别名

2-(ホスホノオキシ)プロペン酸/カリウム,(1:1)

ホスホエノールピルビン酸カリウム

ホスホエノールピルビン酸一カリウム

2-(ホスホノオキシ)プロペン酸/カリウム,(1:1)物理性質

融点	175 °C (dec.)(lit.)
貯蔵温度	2-8°C
溶解性	メタノール（微量）、水（微量）
外見	個体
色	White to off-white
水溶解度	水に溶ける。メタノールにわずかに溶ける。
Sensitive	Hygroscopic
BRN	4603446
CAS データベース	4265-07-0(CAS DataBase Reference)
EPAの化学物質情報	2-Propenoic acid, 2-(phosphonooxy)-, monopotassium salt (4265-07-0)

安全性情報

Sフレーズ	24/25
WGK Germany	3
F	3-10
TSCA	Yes
HSコード	29199000

危険有害性情報のコード(GHS)

2-(ホスホノオキシ)プロペン酸/カリウム,(1:1) 価格

製品番号	包装	価格	製品説明	購入
富士フイルム和光純薬株式会社(wako) W01FLCM02738	250mg	￥11900		購入
富士フイルム和光純薬株式会社(wako) W01FLCM02738	10g	￥150600		購入
富士フイルム和光純薬株式会社(wako) W01COBSS-9762	10g	￥82500		購入
富士フイルム和光純薬株式会社(wako) W01COBSS-9762	100g	￥740000		購入
富士フイルム和光純薬株式会社(wako) W01AFAB20358	5g	￥51010	ホスホエノールピルビン酸一カリウム塩, 99%	購入

2-(ホスホノオキシ)プロペン酸/カリウム,(1:1) 化学特性,用途語,生産方法

外観
白色, 結晶性粉末～粉末
説明
Phosphoenolpyruvic acid plays a role in both glycolysis and gluconeogenesis. During glycolysis, it is formed by the action of enolase on 2-phosphoglycerate and is metabolized to pyruvate by pyruvate kinase. One molecule of ATP is formed during its metabolism in this pathway. During gluconeogenesis, it is formed from phosphoenolpyruvate carboxykinase-catalyzed oxaloacetate decarboxylation and GTP hydrolysis. In plants, it is metabolized to form aromatic amino acids and also serves as a substrate for phosphoenolpyruvate carboxylase-catalyzed carbon fixation.
化学的特性
white to light yellow fine crystalline powder
使用
Phosphoenolpyruvic acid monopotassium salt is used in glycolysis and gluconeogeneis. It is used for regeneration of ATP from ADP in enzyme-catalyzed syntheses. It is metabolized by an enzyme namely pyruvate kinase to yield pyruvate. It acts as protection against cell injury induced by oxidative stress and against dysfunction in carbohydrate metabolism.
一般的な説明
Phospho(enol)pyruvic acid (PEP) acts as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase. It is a bifunctional carbohydrate, which exhibits antioxidant property. PEP may be a potential organ preservation agent in clinical transplantation.
純化方法
KPEP is purified via the monocyclohexylamine salt (see next entry). The salt (534mg) in H2O (10mL) is added to Dowex 50Wx4 H+ form (200-400 mesh, 2mL, H2O washed) and stirred gently for 30minutes and filtered. The resin is washed with H2O (6mL), and the combined solutions are adjusted to pH 7.4 with 3N KOH (~1.4mL) and the volume adjusted to 18.4mL with H2O to give a solution of 0.1M KPEP which can be lyophilised to a pure powder and is very good for enzyme work. It has been recrystallised from MeOH/Et2O. [Clark & Kirby Biochemical Preparations 11 103 1966, Wold & Ballou J Biol Chem 227 301 1957, Cherbuliez & Rabinowitz Helv Chim Acta 39 1461 1956, Beilstein 3 IV 977.] The triNa salt [5541-93-5] M 360.0, is purified as follows: the salt (1g) is dissolved in MeOH (40mL) and dry Et2O is added in excess. The white crystals are collected and dried over P2O5 at 20o. [Cramer & Voges Chem Ber 92 952 1959, Beilstein 3 IV 977.]

2-(ホスホノオキシ)プロペン酸/カリウム,(1:1) 上流と下流の製品情報

2-(ホスホノオキシ)プロペン酸/カリウム,(1:1) 生産企業

2-(ホスホノオキシ)プロペン酸/カリウム,(1:1) スペクトルデータ(IR、Raman)

4265-07-0, 2-(ホスホノオキシ)プロペン酸/カリウム,(1:1) キーワード

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