マレイン酸アセプロマジン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H301：飲み込むと有毒

  H336：眠気やめまいのおそれ

マレイン酸アセプロマジン 価格

マレイン酸アセプロマジン 化学特性,用途語,生産方法

• 外観

  黄色, 結晶～粉末

• 溶解性

  エタノール及びアセトンに溶ける。

• 効能

  鎮静薬 (獣医薬)

• 説明

  Acepromazine is a phenothiazine antipsychotic, analog of chlorpromazine , and a dopamine receptor antagonist. It also binds to muscarinic receptors in rat brain (IC₅₀ = 350 nM) and inhibits contractions of guinea pig ileum induced by acetylcholine (; IC₅₀ = 840 nM). Acepromazine inhibits morphine-induced vomiting in dogs. It also inhibits development of a conditioned avoidance response, unconditioned escape response, and catalepsy in rats (ED₅₀s = 0.98, 3.1, and 17 mg/kg, respectively). Formulations containing acepromazine have been used as tranquilizers and anesthetics premedicant in small and large animal veterinary care.

• 化学的特性

  Yellow Crystalline Solid

• 使用

  Acepromazine maleate has been used:
  
  • as a component of anesthesia cocktail to test its effects on behavioral changes in rats
  • as a component of anesthesia cocktail to study its effects on lung resistance of rats
  • as an anti-psychotic pharmaceutical agent to study its cytotoxic effects on malignant glioma in glioblastoma (GBM) cells
  
  

• 安全性プロファイル

  Poison by ingestion, subcutaneous,and intravenous routes. When heated to decomposition itemits highly toxic fumes of NOx and SOx.

マレイン酸アセプロマジン 上流と下流の製品情報

マレイン酸アセプロマジン 生産企業

Global(162)Suppliers

マレイン酸アセプロマジン スペクトルデータ(¹HNMR)

3598-37-6, マレイン酸アセプロマジン キーワード