ビス(N-フェニルカルバミド酸)3-ピペリジノ-1,2-プロパンジイル

ビス(N-フェニルカルバミド酸)3-ピペリジノ-1,2-プロパンジイル 化学特性,用途語,生産方法

• Originator

  Diothane Hydrochloride,HMR

• Manufacturing Process

  15.0 g phenylisocyanate in 100 ml of anhydrous ether are added to 10 g of N- (1,2-dihydroxypropyl)-piperidine (prepared from glycide and piperidine) and the solution boiled for two hours, after which it is cooled and saturated with dry hydrogen chloride gas. The ether layer is then decanted off and the remaining insoluble product is dissolved in a hot mixture of acetone and ethyl acetate which on cooling precipitates white crystals of the hydrochloride of the ester of 1,2-propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate); MP 197°- 198°C. A base form may be prepared by adding an equivalent of triethyl amine.

• Therapeutic Function

  1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate) (ester), hydrochloride

ビス(N-フェニルカルバミド酸)3-ピペリジノ-1,2-プロパンジイル 上流と下流の製品情報

ビス(N-フェニルカルバミド酸)3-ピペリジノ-1,2-プロパンジイル 生産企業

Global(14)Suppliers

101-08-6, ビス(N-フェニルカルバミド酸)3-ピペリジノ-1,2-プロパンジイル キーワード