P-(3-アミノプロピル)-P-(ジエトキシメチル)ホスフィン酸

P-(3-アミノプロピル)-P-(ジエトキシメチル)ホスフィン酸 価格

P-(3-アミノプロピル)-P-(ジエトキシメチル)ホスフィン酸 化学特性,用途語,生産方法

• 使用

  CGP 35348 hydrate has been used as a γ-aminobutyric acid-B (GABA_B) receptor inhibitor:
  
  • to study its effects on intrinsic optical signal (IOS) in rat hippocampus
  • alone or in combination with sodium salicylate to study its effects on auditory responses in the rat′s dorsal cortex of rat
  • to study its effects on hepatocellular carcinoma cells (HCC)
  
  

• 生物活性

  Selective, brain penetrant GABA B receptor antagonist (IC 50 = 34 μ M as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors.

• Biochem/physiol Actions

  CGP 35348 is a γ-aminobutyric acid-B (GABAB) receptor antagonist. It has a higher affinity towards post-versus presynaptic receptors that can penetrate the blood-brain barrier.

P-(3-アミノプロピル)-P-(ジエトキシメチル)ホスフィン酸 上流と下流の製品情報

P-(3-アミノプロピル)-P-(ジエトキシメチル)ホスフィン酸 生産企業

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P-(3-アミノプロピル)-P-(ジエトキシメチル)ホスフィン酸 スペクトルデータ(¹HNMR)

123690-79-9, P-(3-アミノプロピル)-P-(ジエトキシメチル)ホスフィン酸 キーワード