(+)-4-コレステン-3-オン

危険有害性情報のコード(GHS)

(+)-4-コレステン-3-オン 価格

MSDS Information

• (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

(+)-4-コレステン-3-オン 化学特性,用途語,生産方法

• 外観

  白色～微黄色、結晶性粉末～粉末。

• 説明

  Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol. It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 μg/ml. Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland. It has been used as synthetic intermediate in the synthesis of steroids.

• 化学的特性

  white to light yellow crystals or powder

• 使用

  4-Cholesten-3-one is used as a chiral building block for proteomics research. It is an intestinal metabolite of cholesterol and exhibits an anti-obesity effect on animals.

• 一般的な説明

  Cholestenone is a cholesterol metabolite and analog, which substitutes membrane cholesterol and elevates membrane fluidity.

(+)-4-コレステン-3-オン 上流と下流の製品情報

(+)-4-コレステン-3-オン 生産企業

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(+)-4-コレステン-3-オン スペクトルデータ(¹HNMR、¹³CNMR、IR1、IR2、MS、Raman)

601-57-0, (+)-4-コレステン-3-オン キーワード