24-メチル-5,7,18,20-テトラオキサ-13λ5-アザヘキサシクロ[11.11.0.02,10.04,8.015,23.017,21]テトラコサ-1(13),2,4(8),9,14,16,21,23-オクタエン-13-イリウム

24-メチル-5,7,18,20-テトラオキサ-13λ5-アザヘキサシクロ[11.11.0.02,10.04,8.015,23.017,21]テトラコサ-1(13),2,4(8),9,14,16,21,23-オクタエン-13-イリウム 化学特性,用途語,生産方法

• 説明

  This quaternary alkaloid is present in Cop tis japonica and has been isolated as the tetrahydro base, colourless prisms from EtOH with m.p. 2l2-3°C, oxidized by iodine in EtOH to worenine iodide. The latter forms yellow crystals from which the corresponding chloride may be obtained in the form of orange-yellow prisms, m.p. 295°C (dec.).

• 使用

  Worenine is used in the a flurophore switched probe which aids in correction of an abasic site (AP site) caused by the removal of a damaged base in DNA

• 参考文献

  Kitasato., J. Pharm. Soc., Japan, No. 542, 48 (1927) Kitasato., Acta Phytochimica, 3,210 (1927)

24-メチル-5,7,18,20-テトラオキサ-13λ5-アザヘキサシクロ[11.11.0.02,10.04,8.015,23.017,21]テトラコサ-1(13),2,4(8),9,14,16,21,23-オクタエン-13-イリウム 生産企業

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