(3β-[2-(ジエチルアミノ)エトキシ]アンドロスタ-5-エン-17-オン)·塩酸塩

(3β-[2-(ジエチルアミノ)エトキシ]アンドロスタ-5-エン-17-オン)·塩酸塩 価格

(3β-[2-(ジエチルアミノ)エトキシ]アンドロスタ-5-エン-17-オン)·塩酸塩 化学特性,用途語,生産方法

• 外観

  白色〜わずかにうすい褐色, 結晶〜粉末

• 溶解性

  水溶状：4mg/mL(全溶)

• 使用

  U 18666A is a cell-permeable amphiphilic amino-steroid.

• 一般的な説明

  A cell-permeable, amphiphilic amino-steroid that alters intracelluar membrane protein trafficking by impairing intracellular biosynthesis and transport of LDL-derived cholesterol. Reported to exert its effects via the inhibition of 2,3-oxidosqualene-lanosterol cyclase activity. Also reported to inhibit the activity of Δ⁸-sterol isomerase.

• 生物活性

  Inhibitor of cholesterol synthesis and cellular transport, and weak inhibitor of hedgehog (Hh) signaling. Reduces serum sterol levels in rats in vivo .

(3β-[2-(ジエチルアミノ)エトキシ]アンドロスタ-5-エン-17-オン)·塩酸塩 生産企業

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