(5-フェニル-2-ウレイド)チオフェン-3-カルボキサミド

(5-フェニル-2-ウレイド)チオフェン-3-カルボキサミド 価格

(5-フェニル-2-ウレイド)チオフェン-3-カルボキサミド 化学特性,用途語,生産方法

• 説明

  Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC₅₀ = 13 nM). It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses.

• 使用

  (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE is an inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM). It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses.

(5-フェニル-2-ウレイド)チオフェン-3-カルボキサミド 生産企業

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