(5Z,8Z,11Z,14Z)-5,8,11,14-イコサテトラエン酸メチル

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H304：飲み込んで気道に侵入すると生命に危険のおそ れ

  H315：皮膚刺激

  H336：眠気やめまいのおそれ

  H410：長期的影響により水生生物に非常に強い毒性

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P273：環境への放出を避けること。

  P301+P310：飲み込んだ場合：直ちに医師に連絡すること。

  P331：無理に吐かせないこと。

  P501：内容物/容器を．．．に廃棄すること。

(5Z,8Z,11Z,14Z)-5,8,11,14-イコサテトラエン酸メチル 価格

(5Z,8Z,11Z,14Z)-5,8,11,14-イコサテトラエン酸メチル 化学特性,用途語,生産方法

• 使用

  Arachidonic acid is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool. Arachidonic acid content is frequently measured by the saponification of the lipid fraction followed by methyl esterification and gas chromatographic analysis of the resulting FAME (fatty acid methyl ester) compounds. Arachidonic acid methyl ester can also be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate.

• 定義

  ChEBI: A fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol.

• Biochem/physiol Actions

  Unlike most unsaturated fatty acid methyl esters, methyl arachidonate is a potent activator of protein kinase C at 550μM. At the low end of the effective concentration range, the effect is due to cyclooxygenase products, while lipoxygenase products mediate the effect at higher concentrations.

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