Originator
Chlorbenzoxamine,Shanghai
Definition
ChEBI: Chlorbenzoxamine is a diarylmethane.
Manufacturing Process
A mixture of 0.1 mol of 1-m-methylbenzyl-4-(2-hydroxyethyl)-piperazine and
0.1 mol of o-chlorobenzhydrile chloride was heated at 160°C for 3 hours. After
cooling the product obtained was dissolved in benzene. The solution was
washed with 20% aqueous solution of sodium carbonate and then with water.
Chlorbenzoxamine was distilled in vacuo, B.P. 240°C/0.1 mm Hg. Yield 50%.
Therapeutic Function
Anticholinergic, Antiulcer
