ChemicalBook > CAS DataBase List > 4-Cyclohexylphenol
4-Cyclohexylphenol
4-Cyclohexylphenol
- CAS No.1131-60-8
- Chemical Name:4-Cyclohexylphenol
- CBNumber:CB9764431
- Molecular Formula:C12H16O
- Formula Weight:176.25
- MOL File:1131-60-8.mol
4-Cyclohexylphenol Property
- Melting point 130-135°C
- Boiling point 213-215°C
- Density 0.9452 (rough estimate)
- vapor pressure 0.823-3.6Pa at 25℃
- refractive index 1.5415 (estimate)
- storage temp. Inert atmosphere,Room Temperature
- pka 10.15±0.13(Predicted)
- form Solid:flakes
- color White to Light yellow to Light orange
- Water Solubility 66.66mg/L(25 ºC)
- Dielectric constant 4.0(54℃)
- LogP 4.22-4.33
- Indirect Additives used in Food Contact Substances CYCLOHEXYLPHENOL, P-
- FDA 21 CFR 175.300
- CAS DataBase Reference 1131-60-8(CAS DataBase Reference)
- FDA UNII M5536IXU6K
- NIST Chemistry Reference Phenol, 4-cyclohexyl-(1131-60-8)
- EPA Substance Registry System Phenol, 4-cyclohexyl- (1131-60-8)
Safety
- Hazard Codes :Xi,N
- Risk Statements :20/21/22-36/37/38-50/53-41-37/38
- Safety Statements :26-36/37/39-61-60-39
- Hazard Note :Irritant
- HS Code :2907199090
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H332-H335
- Precautionary statements P280-P305+P351+P338-P310
4-Cyclohexylphenol Price
More Price(1)
- Brand: TCI Chemicals (India)
- Product number: C0733
- Product name : 4-Cyclohexylphenol
- Purity: min. 98.0 %
- Packaging: 25G
- Price: ₹8600
- Updated: 2022/05/26
- Buy: Buy
4-Cyclohexylphenol Chemical Properties,Usage,Production
- Uses 4-Cyclohexylphenol is a derivative of Cyclohexylphenol (CHP), which is widely used in the preparation of dyes, resins, and biocides[2]. 4-Cyclohexylphenol labelled with 35s can be used for metabolic studies[3].
-
Synthesis
4-Cyclohexylphenol is obtained by hydroalkylation of phenol using phenol as a raw material in the presence of a palladium catalyst and a molten salt (NaCl-AlCl3)[1]. The specific synthesis steps are as follows:
The hydroalkylation of phenol in the presence of palladium catalyst and fused salt (NaCl-AlCl3) under hydrogen pressure was carried out. By using 1% Pd-Al2O3 (1 g) and the fused salt (1 : 1 mol ratio, 6 g), 4-cyclohexylphenol was obtained selectively from 1 (30 g) in a yield of 31.9% at 120°C for 4.5 h.
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References
[1] T. KAMIYAMA; M. I; S Enomoto. Hydroalkylation of phenol to cyclohexylphenol in the presence of Pd-Al2O3 and NaCl-AlCl3 under hydrogen pressure.[J]. Chemical & pharmaceutical bulletin, 1986. DOI:10.1248/CPB.34.450.
[2] S. GUTIéRREZ-RUBIO . Synthesis of cyclohexylphenol via phenol hydroalkylation using Co2P/zeolite catalysts[J]. Catalysis Today, 2022. DOI:10.1016/j.cattod.2021.11.039.
[3] D.J. HEARSE; Gillian M P; A H Olavesen. The preparation and characterization of a series of 35S-labelled aryl sulphate esters for metabolic studies[J]. Biochemical pharmacology, 1969. DOI:10.1016/0006-2952(69)90022-7.
4-Cyclohexylphenol Preparation Products And Raw materials
Raw materials
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