1,2-Distearoyl-sn-glycero-3-phosphatidic acid, sodium salt

Description

1,2-Distearoyl-sn-glycero-3-phosphate is a phospholipid containing a phosphatidic acid head group and 18:0 fatty acids at the sn-1 and sn-2 positions of the glycerol backbone. This negatively charged phospholipid has been used to study the dynamics of model lipid bilayers.

Uses

Coatsome MA 8080LS is used as an ultrasound contrast agent for determining cancer therapy effectiveness and adjusting treatment protocol.

References

[1] SHANGHAO LI. Head Groups of Lipids Govern the Interaction and Orientation between Graphene Oxide and Lipids[J]. The Journal of Physical Chemistry C, 2013, 117 1: 16150-16158. DOI: 10.1021/jp405991q
[2] MANALI BHAGAT  Stavroula S. Membrane Heterogeneities and Fusogenicity in PhosphatidylcholinePhosphatidic Acid Rigid Vesicles as a Function of pH and Lipid Chain Mismatch[J]. Langmuir, 2009, 26 3: 1666-1673. DOI: 10.1021/la9026283