Description
Form: Colorless liquid
Uses
Diofenolan is a pesticide, an insect growth regulator. Diofenolan has been developed as a Juvenile hormone agonist for insect pest control
Production Methods
Diofenolan is commercially synthesised through a process begins with the preparation of a 4-phenoxyphenol intermediate, which is reacted with a chloromethyl-substituted 1,3-dioxolane under basic conditions to form the ether linkage. This reaction typically uses solvents like dichloromethane and bases such as potassium carbonate, with temperature control to ensure regioselectivity and minimize side reactions.
Mechanism of action
Insect growth retardant, moulting inhibitor with juvenile hormone activity
Toxicity evaluation
Acute oral LD
50 for rats: >5,000 mg/kg
Pesticide Type
Insecticide; Insect Growth Regulator
