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NICOTINIC ACID MONONUCLEOTIDE

NICOTINIC ACID MONONUCLEOTIDE Structure
NICOTINIC ACID MONONUCLEOTIDE
  • CAS No.321-02-8
  • Chemical Name:NICOTINIC ACID MONONUCLEOTIDE
  • CBNumber:CB9670381
  • Molecular Formula:C11H14NO9P
  • Formula Weight:335.2
  • MOL File:321-02-8.mol
NICOTINIC ACID MONONUCLEOTIDE Property
  • Melting point >115°C (dec.)
  • storage temp. −20°C
  • solubility Methanol (Slightly, Heated), Water(Slightly)
  • form Solid
  • color White to Off-White
  • biological source animal
  • Stability Hygroscopic
  • InChI InChI=1/C11H14NO9P/c13-8-7(5-20-22(17,18)19)21-10(9(8)14)12-3-1-2-6(4-12)11(15)16/h1-4,7-10,13-14H,5H2,(H2-,15,16,17,18,19)/t7-,8-,9-,10-/s3
  • InChIKey JOUIQRNQJGXQDC-NLNRFTKUNA-N
  • SMILES [C@@H]1([C@H](O)[C@H](O)[C@@H](COP([O-])(=O)O)O1)[N+]1C=CC=C(C(=O)O)C=1 |&1:0,1,3,5,r|
  • UNSPSC Code 12352106
  • NACRES NA.79
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

NICOTINIC ACID MONONUCLEOTIDE Chemical Properties,Usage,Production

  • Uses A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.
  • Biological Activity Nicotinic acid mononucleotide (NaMN) may be used to study the relationship between the phosphate-responsive signaling (PHO) pathway and nicotine adenine dinucleotide (NAD(+)) metabolism in yeast. Nicotinate mononucleotide is a substrate for NMN/NaMN adenylyltransferase (NMNAT) and nicotinate mononucleotide adenylyltransferase. NaMN amidation results in the synthesis of nicotinamide mononucleotide(NMN), which is further converted to NAD cofactor.
  • Synthesis Nicotinic acid mononucleotide is prepared by the reaction of 2,3-dicarboxypyridine and 5-phosphoribosyl-1-pyrophosphate. The steps are as follows:
    With phosphoribosyl pyrophosphate-quinolinate phosphoribosyltransferase; magnesium chloride In aq. phosphate buffer at 37℃; for 6h; pH=7.0; Enzymatic reaction.
    Nicotinic acid mononucleotide synthesis
NICOTINIC ACID MONONUCLEOTIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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NICOTINIC ACID MONONUCLEOTIDE Spectrum
321-02-8, NICOTINIC ACID MONONUCLEOTIDERelated Search:
  • Amines
  • Oxidation-Reduction
  • Enzymes, Inhibitors, and Substrates
  • Cofactors
  • Pharmaceuticals
  • Nucleotides
  • Nicotine Derivatives
  • Intermediates & Fine Chemicals
  • Bases & Related Reagents
  • Aromatics
  • 杂质对照品
  • 抑制剂
  • 生化试剂
  • 医用原料
  • 化工原料
  • BioChemical
  • Biochemicals and Reagents
  • Oxidation-Reduction
  • Enzymes, Inhibitors, and Substrates
  • Cofactors
  • C11H14NO9P
  • C11H15NO9P
  • 化合物 NICOTINIC ACID MONONUCLEOTIDE
  • Β-烟酸单核苷酸
  • 化合物 T19477
  • 烟酸单核苷酸
  • Β-NICOTINICACIDMONONUCLEOTIDE
  • 邻苯二甲酸杂质18
  • 烟酸单核苷酸(CAS 321-02-8)
  • 321-02-8
  • b-Nicotinic Acid Mononucleotide
  • β-Nicotinic Acid Mon
  • 3-Carboxy-1-methylpyridiniumiodid
  • 3-Carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium
  • β-NicotinicAcidMononucleotide
  • β-NaMN
  • Nicotinic Mononucleotide
  • Nicotinic Acid Ribotide
  • Nicotinic Acid Ribonucleotide
  • Nicotinate Ribonucleotide
  • 3-Carboxy-1-β-D-ribofuranosylpyridiniuM Hydroxide 5'-Phosphate Inner Salt
  • 3-Carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)pyridiniuM Inner Salt
  • 3-Carboxylato-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium
  • 1-[3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]pyridine-5-carboxylate
  • NICOTINIC ACID MONONUCLEOTIDE
  • nicotinatemononucleotide

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