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ANTIMYCIN A1

ANTIMYCIN A1 Structure
ANTIMYCIN A1
  • CAS No.642-15-9
  • Chemical Name:ANTIMYCIN A1
  • CBNumber:CB9479432
  • Molecular Formula:C28H40N2O9
  • Formula Weight:548.63
  • MOL File:642-15-9.mol
ANTIMYCIN A1 Property
  • Melting point 149.5℃
  • alpha D26 +76° (c = 1 in chloroform)
  • Boiling point 620.81°C (rough estimate)
  • Density 1.2468 (rough estimate)
  • refractive index 1.5800 (estimate)
  • storage temp. −20°C
  • solubility DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
  • form A solid
  • FDA UNII 8771CCP8LT
Safety
  • Hazard Codes  :T
  • Risk Statements  :23/24/25
  • Safety Statements  :36/37/39-45
  • RIDADR  :3172
  • RTECS  :NY1503500
  • HazardClass  :6.1(a)
  • PackingGroup  :II
  • NFPA 704:
    0
    4 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301-H311-H331
  • Precautionary statements P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501

ANTIMYCIN A1 Chemical Properties,Usage,Production

  • Description Antimycin A1 is an active component of the antimycin A antibiotic complex. It inhibits electron transport and is active against the plant pathogenic fungus G. cingulate. Antimycin A1 (3.3-160 μM) induces the synthesis of carotenoids in M. marinum. It also inhibits ATP-citrate lyase (Ki = 29.5 μM).
  • Chemical Properties Crystals. Soluble in alcohol, ether, acetone, and chloroform; slightly soluble in benzene, carbon tetrachloride, and petroleum ether; insoluble in water.
  • Chemical Properties Antimycin (A3C26H36N2O9) and (Antimycin A1) C28H40N2O9 are crystalline solids.
  • Uses Antimycin A1 is the most hydrophobic of the four analogues of the antimycin A complex. Like all antimycins, antimycin A1 exhibits potent antifungal, anthelmintic, insecticidal, antiviral and antitumor activity across a range of bioassays. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of individual members of the complex as bioprobes. Antimycin A1 inhibits angiogenesis via a decrease in VEGF production caused by inhibition of HIF-1a activation.
  • Uses Experimentally as fungicide, insecticide, miticide.
  • Definition An antibiotic substance said to have strong fungicidal properties.
  • Potential Exposure Specific uses for antimycin A were not found, however, antimycin A1, and antimycin A3 are reported to be antibiotic substances produced by streptomyces for use as a fungicide, possible insecticide and miticide. Registered as a pesticide in the U.S.
  • Shipping UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
ANTIMYCIN A1 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTIMYCIN A1 Suppliers
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ANTIMYCIN A1 Spectrum
642-15-9, ANTIMYCIN A1Related Search:
  • 抑制剂
  • 实验室通用药物
  • 生物化学品
  • 生化试剂
  • 微生物代谢物
  • C28H40N2O9
  • C16H21NO2
  • 安霉素A1
  • 抗黴素A1,二氢沙米丁
  • 抗霉素A1
  • 二氢沙米丁
  • 二氫沙米汀
  • 抗黴素A1
  • 642-15-9
  • 1,5-Dioxonane butanoic acid deriv.
  • 3-methylbutyric acid [3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-4,9-diketo-2,6-dimethyl-1,5-dioxonan-7-yl] ester
  • [3-[(3-formamido-2-hydroxy-phenyl)carbonylamino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate
  • [3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate
  • 3-Methylbutyric acid 3-[[3-(formylamino)-2-hydroxybenzoyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
  • 3-Methylbutanoic acid 3-[[3-(formylamino)-2-hydroxybenzoyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
  • 3-(3-formamidosalicylamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl isovalerate
  • ANTIMYCIN A1
  • isovalericacid,8-esterwith3-formamido-n-(7-hexyl-8-hydroxy-4,9-dimethyl-2,6
  • -dioxo-1,5-dioxonan-3-yl)salicylamide
  • dihydrosamidin

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