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N-(Benzyloxycarbonyloxy)succinimide

N-(Benzyloxycarbonyloxy)succinimide Structure
N-(Benzyloxycarbonyloxy)succinimide
  • CAS No.13139-17-8
  • Chemical Name:N-(Benzyloxycarbonyloxy)succinimide
  • CBNumber:CB9474578
  • Molecular Formula:C12H11NO5
  • Formula Weight:249.22
  • MOL File:13139-17-8.mol
N-(Benzyloxycarbonyloxy)succinimide Property
  • Melting point 80-82 °C(lit.)
  • Boiling point 392.32°C (rough estimate)
  • Density 1.3189 (rough estimate)
  • refractive index 1.5560 (estimate)
  • Flash point 81°C
  • storage temp. Keep in dark place,Inert atmosphere,2-8°C
  • solubility acetone: 0.1 g/mL, clear
  • form Fine Crystalline Powder
  • color White to off-white
  • Decomposition 81 ºC
  • Sensitive Moisture Sensitive
  • BRN 1387927
  • Stability Stable. Moisture sensitive.
  • CAS DataBase Reference 13139-17-8(CAS DataBase Reference)
  • UNSPSC Code 12352005
  • NACRES NA.22
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
N-(Benzyloxycarbonyloxy)succinimide Price More Price(10)
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  • Product name : N-(Benzyloxycarbonyloxy)succinimide
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  • Product number: 227781
  • Product name : N-(Benzyloxycarbonyloxy)succinimide
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  • Product number: 227781
  • Product name : N-(Benzyloxycarbonyloxy)succinimide
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N-(Benzyloxycarbonyloxy)succinimide Chemical Properties,Usage,Production

  • Chemical Properties white crystal powde
  • Uses N-(Benzyloxycarbonyloxy)succinimide (Cbz-OSu) is a common reagent for the carboxybenzyl protection of amines. This reaction is one of the key synthetic steps in the synthesis of:
    • Enantiomers of cyclic methionine analogs viz, (R)-and (S)-3-aminotetrahydrothiophene- 3-carboxylic acid.
    • 1′-H-Spiro-(indoline-3,4′-piperidine) and its derivatives.
    • Total synthesis of (-)-diazonamide A. and (-)-sanglifehrin A.

    Cbz-OSu is widely employed to protect amino acid residues in peptide synthesis. It can also be used in N-trans diprotection of cyclen regioselectively.
  • Uses N-(N-Benzyloxycarbonyloxy)succinimide is a reagent used in the preparation of peptide thioacids view peptide precursors. Also used in the preparation of amino glycoside derivatives for the function of topoisomerase for both human and bacterial inhibition.
  • Uses Reagents for the selective introduction of the Z-protecting group into amino compounds
N-(Benzyloxycarbonyloxy)succinimide Preparation Products And Raw materials
Raw materials
Preparation Products
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N-(Benzyloxycarbonyloxy)succinimide Spectrum
13139-17-8, N-(Benzyloxycarbonyloxy)succinimideRelated Search:
  • Cbz-Amino acid series
  • Synthetic Organic Chemistry
  • Protective Reagents (Peptide Synthesis)
  • Peptide Synthesis
  • N-Substituted Succinimides
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • Condensation & Active Esterification
  • Biochemistry
  • N-Protecting Reagents
  • Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
  • Amino Acid Derivatives
  • Peptide coupling agents
  • Medical Intermediates
  • 苯甲氧羰酰琥珀酰亚胺
  • 高端化学
  • 原料药
  • 生物化工-氨基酸及其衍生物
  • 多肽-美容肽
  • 精细化工品
  • 通用生化试剂-氨基酸
  • 偶联剂及保护剂
  • 有机化工
  • 有机化工原料
  • 原料
  • 生化试剂-氨基酸类
  • 其他生化试剂
  • 化学试剂
  • 化工原料
  • 医用原料
  • 化工中间体
  • 氨基保护
  • 氨基酸类
  • 医药原料
  • 胺
  • 通用试剂
  • 保护剂
  • 耦合试剂
  • 中间体
  • 氨基酸
  • 保护试剂
  • 有机砌块
  • 医药中间体
  • 多肽
  • 保护氨基酸
  • 芳烃
  • Synthetic Reagents
  • Protection and Derivatization
  • Protecting and Derivatizing Reagents
  • Others
  • Peptide Synthesis
  • Condensation & Active Esterification
  • Protective Reagents (Peptide Synthesis)
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Succinimides
  • 1319-17-8
  • 3139-17-8
  • 苯甲氧羰酰琥珀酰亚胺/N-苄氧羰氧基丁二酰亚胺/Z-OSU/CBZ-OSU
  • N-苄琥珀酰亚胺碳酸酯

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