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TFLLR-NH2

TFLLR-NH2 Structure
TFLLR-NH2
  • CAS No.197794-83-5
  • Chemical Name:TFLLR-NH2
  • CBNumber:CB9464681
  • Molecular Formula:C31H53N9O6
  • Formula Weight:647.81
  • MOL File:197794-83-5.mol
TFLLR-NH2 Property
  • Density 1.31±0.1 g/cm3(Predicted)
  • storage temp. Desiccate at -20°C
  • pka 12.10±0.45(Predicted)
  • form Powder
  • Water Solubility Soluble to 1 mg/ml in water
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

TFLLR-NH2 Chemical Properties,Usage,Production

  • Uses TFLLR-NH2 is a PAR-1 activator.
  • in vivo

    Injection of TF-NH2 into the rat paw stimulates a marked and sustained oedema. An NK1R antagonist and ablation of sensory nerves with capsaicin inhibit oedema by 44% at 1?h and completely by 5?h. In wild-type but not PAR1?/? mice, TF-NH2 stimulates Evans blue extravasation in the bladder, oesophagus, stomach, intestine and pancreas by 2–8 fold. Extravasation in the bladder, oesophagus and stomach is abolished by an NK1R antagonist[1]. TFp-NH2 produces notable contraction at 3-50 μM and relaxation at 0.3-50 μM, in the absence of apamin. The concentration-response curve for TFp-NH2-induced contraction is remarkably shifted left, when the TFp-NH2-induced relaxation is blocked by apamin at 0.1 μM[3].

  • IC 50 PAR1: 1.9 μM (EC50)
  • storage -20°C
TFLLR-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
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TFLLR-NH2 Spectrum
197794-83-5, TFLLR-NH2Related Search:
  • Peptide Receptors
  • Proteinase-activated receptor (PAR)
  • 抑制剂
  • 多肽
  • 标准品
  • C31H53N9O6
  • 血酶受体
  • TFLLR-NH2,PAR1激动剂多肽
  • 化合物TFLLR-NH2(2TFA)
  • 197794-83-5
  • PAR-1 agonist/ TRAP6
  • TFLLR-NH2, PAR1 agonist peptide
  • (Thr?)-PAR-1 (1-5) amide (human) trifluoroacetate salt
  • 1313730-19-6/197794-83-5
  • TFLLR NH2 2TFA(197794 83 5(free base)),TFLLR-NH-2 2TFA(197794-83-5(free base)),TFLLRNH2 2TFA(197794835(free base))
  • TFLLR-NH2 2TFA(197794-83-5(free base))
  • L-Argininamide, L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-
  • (Thr1)-PAR-1 (1-5) amide (human)
  • TFLLR
  • TFLLR-NH2(2TFA)
  • (2S)-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
  • REF DUPL: H-Thr-Phe-Leu-Leu-Arg-NH2
  • HYBRIDE HUMAN-XENOPE
  • TFLLRaMide, (Thr1)-TRAP-5 aMide, (Thr1)-PAR-1 (1-5) aMide (huMan)
  • TFLLR-NH2 Protease-Activated Receptor 1 (PAR1) Agonist
  • (Thr1)-TRAP-5 amide
  • TFLLR-NH2
  • TFLLR-AMIDE
  • THROMBIN RECEPTOR (PAR-1), HYBRIDE HUMAN-XENOPE
  • THR-PHE-LEU-LEU-ARG-NH2
  • H-THR-PHE-LEU-LEU-ARG-NH2

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