ChemicalBook > CAS DataBase List > BTS
BTS
BTS
- CAS No.1576-37-0
- Chemical Name:BTS
- CBNumber:CB9457528
- Molecular Formula:C14H15NO2S
- Formula Weight:261.34
- MOL File:1576-37-0.mol
BTS Property
- Melting point 115 °C
- Boiling point 419.1±48.0 °C(Predicted)
- Density 1.204±0.06 g/cm3(Predicted)
- storage temp. Keep in dark place,Sealed in dry,Room Temperature
- solubility Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly)
- form White crystalline solid
- pka 11.54±0.30(Predicted)
- color White to Off-White
- Sensitive Light Sensitive
- CAS DataBase Reference 1576-37-0(CAS DataBase Reference)
- UNSPSC Code 12352200
- NACRES NA.77
Safety
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319-H335
- Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a
BTS Price
More Price(5)
- Brand: Sigma-Aldrich(India)
- Product number: 203895
- Product name : BTS - CAS 1576-37-0 - Calbiochem
- Purity: A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC?? = ~ 5 μM) and reversibly blocks the gliding motility.
- Packaging: 5MG
- Price: ₹16670.01
- Updated: 2022/06/14
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: B3082
- Product name : N-Benzyl-p-toluenesulfonamide
- Purity:
- Packaging: 5G
- Price: ₹6800
- Updated: 2022/05/26
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: B3082
- Product name : N-Benzyl-p-toluenesulfonamide
- Purity:
- Packaging: 25G
- Price: ₹9900
- Updated: 2022/05/26
- Buy: Buy
- Brand: ALFA India
- Product number: ALF-J64910-MA
- Product name : N-Benzyl-p-toluenesulfonamide
- Purity:
- Packaging: 10mg
- Price: ₹14685
- Updated: 2022/05/26
- Buy: Buy
- Brand: ALFA India
- Product number: ALF-J64910-LB0
- Product name : N-Benzyl-p-toluenesulfonamide
- Purity:
- Packaging: 5mg
- Price: ₹11770
- Updated: 2022/05/26
- Buy: Buy
BTS Chemical Properties,Usage,Production
- Description BTS is an inhibitor of skeletal muscle myosin II ATPase activity that reduces the affinity of ADP-myosin for actin. It inhibits calcium-stimulated ATPase activity of rabbit muscle myosin subfragment 1 (S1) in an actin-independent manner with an IC50 value of approximately 5 μM. It is selective for calcium-stimulated myosin II over human platelet myosin II, kinesin, pyruvate kinase, and lactate dehydrogenase at 100 μM. BTS (2 μM) inhibits the activity of skeletal muscle myosin, reversibly reducing the sliding velocity of heavy meromyosin in a gliding-filament assay. It inhibits isometric calcium-activated tension in isolated fast-twitch rabbit psoas muscle fibers (IC50 = ~3 μM) but not in isolated slow-twitch rat trabeculae and papillary cardiac muscle. BTS is also an intermediate in the synthesis of sulfonamides.
- Chemical Properties White Solid
- Uses A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II
- Uses A potent inhibitor of calcium-stimulated myosin S1 ATPase
- Definition ChEBI: 4-methyl-N-(phenylmethyl)benzenesulfonamide is a sulfonamide.
- Synthesis Reference(s) The Journal of Organic Chemistry, 28, p. 592, 1963 DOI: 10.1021/jo01037a523
- Biological Activity Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC 50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.
- storage Desiccate at RT
BTS Preparation Products And Raw materials
Raw materials
Preparation Products
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1576-37-0, BTSRelated Search:
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- ATPase
- Inhibitors
- A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~5 μM) and reversibly blocks the gliding motility.
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- 1576-37-0
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- N-Benzyl-p-toluenesulfonamide >
- BTS (N-Benzyl-p-toluenesulfonamide
- Benzenesulfonamide,4-methyl-N-(phenylmethyl)-
- BTS - CAS 1576-37-0 - Calbiochem
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