ChemicalBook > CAS DataBase List > SR-95531
SR-95531
SR-95531
- CAS No.104104-50-9
- Chemical Name:SR-95531
- CBNumber:CB9356638
- Molecular Formula:C15H18BrN3O3
- Formula Weight:368.23
- MOL File:104104-50-9.mol
SR-95531 Property
- Melting point 200 °C(Solv: ethanol (64-17-5))
- storage temp. Store at RT
- solubility DMSO: 30 mg/mL
- form solid
- color white
- Water Solubility water: 25mM
- EWG's Food Scores 1
- FDA UNII 99460MG420
- UNSPSC Code 12352200
- NACRES NA.77
Safety
- WGK Germany :3
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H335
- Precautionary statements P261-P280-P305+P351+P338
SR-95531 Price
More Price(3)
- Brand: Sigma-Aldrich(India)
- Product number: S106
- Product name : SR-95531
- Purity: ≥98% (HPLC), powder
- Packaging: 10MG
- Price: ₹18640.65
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: S106
- Product name : SR-95531
- Purity: ≥98% (HPLC), powder
- Packaging: 50MG
- Price: ₹62503.55
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: 5.05986
- Product name : SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem
- Purity:
- Packaging: 10MG
- Price: ₹14100
- Updated: 2022/06/14
- Buy: Buy
SR-95531 Chemical Properties,Usage,Production
-
Description
SR 95531 is a derivative of γ-
aminobutyric acid (GABA) that acts as an antagonist of GABAA receptors (Ki = 74- 150 nM). When administered intravenously, it elicits seizures in mice. SR 95531 differs in action from bicuculline in that it antagonizes GABA- induced chloride currents but not those induced by pentobarbitone. It is effective against GABAA receptor isoforms from mice, rats, and humans. - Uses Gabazine Hydrobromide is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites.
- Biological Activity Selective, competitive GABA A receptor antagonist. Displaces [ 3 H]-GABA from rat brain membranes with a K i of 150 nM. Unlike bicuculline, selectively antagonizes GABA-induced Cl - currents with little action on pentobarbitone-induced currents. Also acts as a low affinity glycine receptor antagonist.
- Biochem/physiol Actions SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities.
- storage Room temperature
SR-95531 Preparation Products And Raw materials
Raw materials
Preparation Products
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104104-50-9, SR-95531Related Search:
- GABA/Glycine receptor
- 抑制剂
- 高端化学
- GABA and Glycine Receptor Modulators
- Ligand-Gated Ion Channels
- Ion Channels
- BioChemical
- Cell Signaling and Neuroscience
- Cell Biology
- C15H18N3O3Br
- C15H18BrN3O3
- C15H17N3O3HBr
- 104105-50-9
- 克他命,10 MM DMSO 溶液
- SR95531 (GABAZINE),GABAA拮抗剂
- SR95531 (GABAZINE) (MM/ML),GABAA拮抗剂
- SR-95531,GABA A拮抗剂
- 4-(6-亚氨基-3-(4-甲氧苯基)哒嗪-1(6H)-基)丁酸氢溴酸盐
- 2-(3-羧基丙基)-3-氨基-6-(4-甲氧苯基)吡啶溴化物
- 104104-50-9
- Gabazine, 10 mM in DMSO
- SR95531 (Gabazine), GABAA antagonist
- SR95531 (Gabazine) (mM/ml), GABAA antagonist
- Inhibitor,Gamma-aminobutyric acid Receptor,Gabazine,γ-Aminobutyric acid Receptor,inhibit,SR 95531,GABA Receptor,SR-95531
- GABAZINE
- 4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid
- Gabazine bromide (SR95531)
- SR 95531 hydrobromid
- SR 95531 hydrobromide NEW
- SR-95531
- SR 95531 HYDROBROMIDE
- 6-IMINO-3-(4-METHOXYPHENYL)-1(6H)-PYRIDAZINEBUTANOIC ACID HYDROBROMIDE
- 2-(3-CARBOXYPROPYL)-3-AMINO-6-(4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE
- 2-(3-CARBOXYPROPYL)-3-AMINO-6-(4-METHOXYPHENYL)PYRIDAZINIUM
- GABAZINE BROMIDE
- 4-(6-Imino-3-(4-methoxyphenyl)pyridazin-1(6H)-yl)butanoic acid hydrobromide
- Gabazine Hydrobromide
- 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid monohydrobromide
- 6-Amino-5-methyl-3-(4-methoxyphenyl)-1-pyridaziniumbutyric acid br
- 1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)-, monohydrobromide
- Gabazine, 2-(3-Carboxypropyl)-3-amino-6-(4 methoxyphenyl)pyridazinium bromide