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SR-95531

SR-95531 Structure
SR-95531
  • CAS No.104104-50-9
  • Chemical Name:SR-95531
  • CBNumber:CB9356638
  • Molecular Formula:C15H18BrN3O3
  • Formula Weight:368.23
  • MOL File:104104-50-9.mol
SR-95531 Property
  • Melting point 200 °C(Solv: ethanol (64-17-5))
  • storage temp. Store at RT
  • solubility DMSO: 30 mg/mL
  • form solid
  • color white
  • Water Solubility water: 25mM
  • EWG's Food Scores 1
  • FDA UNII 99460MG420
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P280-P305+P351+P338
SR-95531 Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: S106
  • Product name : SR-95531
  • Purity: ≥98% (HPLC), powder
  • Packaging: 10MG
  • Price: ₹18640.65
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: S106
  • Product name : SR-95531
  • Purity: ≥98% (HPLC), powder
  • Packaging: 50MG
  • Price: ₹62503.55
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 5.05986
  • Product name : SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem
  • Purity: 
  • Packaging: 10MG
  • Price: ₹14100
  • Updated: 2022/06/14
  • Buy: Buy

SR-95531 Chemical Properties,Usage,Production

  • Description SR 95531 is a derivative of γ-aminobutyric acid (GABA) that acts as an antagonist of GABAA receptors (Ki = 74-150 nM). When administered intravenously, it elicits seizures in mice. SR 95531 differs in action from bicuculline in that it antagonizes GABA-induced chloride currents but not those induced by pentobarbitone. It is effective against GABAA receptor isoforms from mice, rats, and humans.
  • Uses Gabazine Hydrobromide is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites.
  • Biological Activity Selective, competitive GABA A receptor antagonist. Displaces [ 3 H]-GABA from rat brain membranes with a K i of 150 nM. Unlike bicuculline, selectively antagonizes GABA-induced Cl - currents with little action on pentobarbitone-induced currents. Also acts as a low affinity glycine receptor antagonist.
  • Biochem/physiol Actions SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities.
  • storage Room temperature
SR-95531 Preparation Products And Raw materials
Raw materials
Preparation Products
SR-95531 Suppliers
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SR-95531 Spectrum
104104-50-9, SR-95531Related Search:
  • GABA/Glycine receptor
  • 抑制剂
  • 高端化学
  • GABA and Glycine Receptor Modulators
  • Ligand-Gated Ion Channels
  • Ion Channels
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • C15H18N3O3Br
  • C15H18BrN3O3
  • C15H17N3O3HBr
  • 104105-50-9
  • 克他命,10 MM DMSO 溶液
  • SR95531 (GABAZINE),GABAA拮抗剂
  • SR95531 (GABAZINE) (MM/ML),GABAA拮抗剂
  • SR-95531,GABA A拮抗剂
  • 4-(6-亚氨基-3-(4-甲氧苯基)哒嗪-1(6H)-基)丁酸氢溴酸盐
  • 2-(3-羧基丙基)-3-氨基-6-(4-甲氧苯基)吡啶溴化物
  • 104104-50-9
  • Gabazine, 10 mM in DMSO
  • SR95531 (Gabazine), GABAA antagonist
  • SR95531 (Gabazine) (mM/ml), GABAA antagonist
  • Inhibitor,Gamma-aminobutyric acid Receptor,Gabazine,γ-Aminobutyric acid Receptor,inhibit,SR 95531,GABA Receptor,SR-95531
  • GABAZINE
  • 4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid
  • Gabazine bromide (SR95531)
  • SR 95531 hydrobromid
  • SR 95531 hydrobromide NEW
  • SR-95531
  • SR 95531 HYDROBROMIDE
  • 6-IMINO-3-(4-METHOXYPHENYL)-1(6H)-PYRIDAZINEBUTANOIC ACID HYDROBROMIDE
  • 2-(3-CARBOXYPROPYL)-3-AMINO-6-(4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE
  • 2-(3-CARBOXYPROPYL)-3-AMINO-6-(4-METHOXYPHENYL)PYRIDAZINIUM
  • GABAZINE BROMIDE
  • 4-(6-Imino-3-(4-methoxyphenyl)pyridazin-1(6H)-yl)butanoic acid hydrobromide
  • Gabazine Hydrobromide
  • 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid monohydrobromide
  • 6-Amino-5-methyl-3-(4-methoxyphenyl)-1-pyridaziniumbutyric acid br
  • 1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)-, monohydrobromide
  • Gabazine, 2-(3-Carboxypropyl)-3-amino-6-(4 methoxyphenyl)pyridazinium bromide