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5-Chlorovaleryl chloride

Description

CAS No.1575-61-7
Chemical Name:5-Chlorovaleryl chloride
CBNumber:CB9348033
Molecular Formula:C5H8Cl2O
Formula Weight:155.02
MOL File:1575-61-7.mol

5-Chlorovaleryl chloride Property

Boiling point 38-39 °C0.15 mm Hg(lit.)
Density 1.206 g/mL at 20 °C
refractive index n20/D 1.464(lit.)
Flash point 195 °F
storage temp. Store below +30°C.
solubility Acetonitrile (Slightly), Chloroform (Sparingly)
form Liquid
color Clear colorless to slightly yellow
Specific Gravity 1.200
PH <7 (H2O, 20℃)
explosive limit 2.0-10.2%(V)
Water Solubility reacts
Sensitive Moisture Sensitive
BRN 1745182
Stability Corrosive, Moisture Sensitive
InChIKey SVNNWKWHLOJLOK-UHFFFAOYSA-N
CAS DataBase Reference 1575-61-7(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

Safety

Hazard Codes :C,T
Risk Statements :22-34-23-23/34
Safety Statements :26-36/37/39-45
RIDADR :UN 3265 8/PG 2
WGK Germany :1
RTECS :YV9108000
F :10-19-21
HazardClass :8
PackingGroup :III
HS Code :29159000

NFPA 704:

	2
3		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H302-H314
Precautionary statements P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338

5-Chlorovaleryl chloride Price More Price(6)

Brand: Sigma-Aldrich(India)
Product number: 125245
Product name : 5-Chlorovaleroyl chloride
Purity: 96%
Packaging: 10G
Price: ₹15826.15
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 125245
Product name : 5-Chlorovaleroyl chloride
Purity: 96%
Packaging: 50G
Price: ₹29054.3
Updated: 2022/06/14
Buy: Buy

Brand: TCI Chemicals (India)
Product number: C1789
Product name : 5-Chlorovaleryl Chloride
Purity: min. 98.0 %
Packaging: 5G
Price: ₹3300
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: C1789
Product name : 5-Chlorovaleryl Chloride
Purity: min. 98.0 %
Packaging: 25G
Price: ₹8700
Updated: 2022/05/26
Buy: Buy

Brand: ALFA India
Product number: ALF-H56237-22
Product name : 5-Chlorovaleroyl chloride, 98%
Purity:
Packaging: 100g
Price: ₹34512
Updated: 2022/05/26
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5-Chlorovaleryl chloride Chemical Properties,Usage,Production

Description 5-Chlorovaleryl chloride is an important synthetic intermediate of pyrazole herbicides. 5-Chloropentanoyl chloride is used as the raw material of 1,1,7-trichloro-1-hepten-3-one, and then the third-generation pyrazole herbicides can be synthesized. Pyrazole herbicides have the characteristics of ultra-efficient herbicidal activity, high selectivity, extremely low mammalian toxicity and good environmental characteristics, and have become a hot spot in the research and development of herbicides in the world in recent years.
Chemical Properties clear colourless to slightly yellow liquid
Uses 5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine. It is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.
Application 5-Chlorovaleryl chloride is an important medicine and pesticide intermediate. It is pharmaceutically mainly for the manufacture of the medicine Cilostazole (Cilostazol) for anti-platelet aggregation, protection of vascular endothelial cells, and atherosclerosis.5-Chlorovaleryl Chloride is also for the production of paddy rice New-type wide-spectrum weedicide pyraclonil (Pyraclonil).
General Description 5-Chlorovaleroyl chloride is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.
Flammability and Explosibility Not classified
Synthesis In the existing process, producing 5-Chlorovaleryl chloride using 1,4-dichlorobutane as raw material requires a three-step reaction. First, 1,4-dichlorobutane and sodium cyanide solution are combined to form 5-chlorovaleronitrile. Then, the prepared 5-chlorovaleronitrile is hydrolyzed in concentrated hydrochloric acid to form 5-chlorovaleric acid. Finally, 5-chlorovaleronitrile reacts with thionyl chloride to generate 5-chlorovaleryl chloride.