ChemicalBook > CAS DataBase List > 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE

2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE

2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Structure
2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE
  • CAS No.19752-61-5
  • Chemical Name:2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE
  • CBNumber:CB9323582
  • Molecular Formula:C12H19BrN2O2
  • Formula Weight:303.2
  • MOL File:19752-61-5.mol
2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Property
  • Melting point 58-61°C
  • Boiling point 352.0±45.0 °C(Predicted)
  • Density 1.267±0.06 g/cm3(Predicted)
  • storage temp. Keep in dark place,Sealed in dry,Room Temperature
  • solubility DCM, Ethyl Acetate, Methanol
  • pka 1.73±0.29(Predicted)
  • form Solid
  • color White
Safety
  • HS Code  :2933998090
  • NFPA 704:
    1
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a

2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Chemical Properties,Usage,Production

  • Uses 5-Bromo-2,4-bis(1,1-dimethylethoxy)pyrimidine is an intermediate in the synthesis of β-Pseudouridine (O839607), an isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA.
  • Synthesis 1.jpg
    5-Bromo-2,4-dichloropyrimidine (10.0 mmol, 2.28 g) is dissolved in dry THF (50 mL). Then a solution of sodium tert-butoxide (25.0 mmol, 2.40 g) in THF (100 mL) is added dropwise at rt and the reaction mixture stirred for 5 h. The reaction is quenched with water (50 mL) and extracted with EtOAc (3 x 50 mL). Purification by flash chromatography yielded the desired product 5 as colorless solid (2.79 g, 92%). 5-Bromo-2,4-di-tert-butoxypyrimidine 5 ,Yield 2.79 g, 92%.
2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Suppliers
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2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Spectrum
19752-61-5, 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINERelated Search:
  • Pyrimidines
  • 高端化学
  • 嘧啶类
  • 5-溴-2,4-二特丁氧基嘧啶
  • 5-溴-2,4-二-(叔丁氧基)嘧啶,95%
  • 5-溴-2,4-二-叔丁氧基嘧啶
  • 2,4-二叔丁氧基-5-溴嘧啶
  • 19752-61-5
  • Oxirane, 2-[14-(phenylMethoxy)ethyl]-
  • Benzaldehyde,4-(4,6-dichloro-1,3,5-triazin-4-yl)-
  • 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE ISO 9001：2015 REACH
  • Pyrimidine, 5-bromo-2,4-bis(1,1-dimethylethoxy)-
  • 5-Bromo-2,4-di-(tert-butoxy)pyrimidine 95%
  • 5-bromo-2,4-bis[(2-methylpropan-2-yl)oxy]pyrimidine
  • 5-BroMo-2,4-bis(1,1-diMethylethoxy)pyriMidine
  • 5-broMo-2,4-bis(tert-butoxy)pyriMidine
  • 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE
  • 2,4-DI-T-BUTOXY-5-BROMO-PYRIMIDINE
  • 5-BROMO-2,4-DI-(TERT-BUTOXY)PYRIMIDINE
  • IFLAB-BB F1371-0151

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