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Potassium thioacetate

CAS No.10387-40-3
Chemical Name:Potassium thioacetate
CBNumber:CB9316520
Molecular Formula:C2H3KOS
Formula Weight:114.21
MOL File:10387-40-3.mol

Potassium thioacetate Property

Melting point 173-176 °C (lit.)
bulk density 500kg/m3
Density 1.58 g/cm3
storage temp. Inert atmosphere,Room Temperature
solubility soluble
form Crystalline Powder, Crystals or Chunks
color White to light brown
Water Solubility soluble
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
Sensitive Air Sensitive & Hygroscopic
BRN 3595448
CAS DataBase Reference 10387-40-3(CAS DataBase Reference)
FDA UNII ZY58K327HN
EPA Substance Registry System Ethanethioic acid, potassium salt (10387-40-3)
UNSPSC Code 12352302
NACRES NA.22

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36-37/39
RIDADR :UN 3335
WGK Germany :3
F :3-9-13-23
TSCA :Yes
HazardClass :9
HS Code :29309070

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Potassium thioacetate Price More Price(8)

Brand: Sigma-Aldrich
Product number: 241776
Product name : Potassium thioacetate
Purity: 98%
Packaging: 25G
Price: ₹2998.53
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 241776
Product name : Potassium thioacetate
Purity: 98%
Packaging: 25G
Price: ₹2998.53
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich
Product number: 241776
Product name : Potassium thioacetate
Purity: 98%
Packaging: 100G
Price: ₹9969.83
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 241776
Product name : Potassium thioacetate
Purity: 98%
Packaging: 100G
Price: ₹9969.83
Updated: 2022/06/14
Buy: Buy

Brand: ALFA India
Product number: ALF-L05405-22
Product name : Potassium thioacetate, 98%
Purity:
Packaging: 100g
Price: ₹10072
Updated: 2022/05/26
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Potassium thioacetate Chemical Properties,Usage,Production

Chemical Properties white to light brown crystalline powder, crystals
Uses Potassium thioacetate is used for palladium mediated coupling with aryl halides and triflates leading to S-arylthioacetates and derivatives. It is also used as a reagent in the conversion of halides to thiols.
Uses Potassium Thioacetate is the potassium salt of Thioacetic Acid, a commonly used reagent in organic synthesis for the introduction of thiol groups in molecules.
Application Potassium thioacetate is an organosulfur compound and a salt with the formula CH3COS−K+. This white, water-soluble solid is used as a reagent for preparing thioacetate esters and other derivatives . It acts as a sulfur source in the synthesis of sulfur-containing organic compounds for the synthesis of heterocycles, polymers, transition-metal ligands, nanoparticles, bioactive compounds and macromolecular inclusion complexes. It is also used for palladium mediated coupling with aryl halides and triflates leading to S-arylthioacetates and derivatives and it is also used as a reagent in the conversion of halides to thiols.
Reactions Thioacetate is also a class of sulfur-containing nucleophiles, of which potassium thioacetate is the most widely used reagent. Potassium thioacetate reacts with organic halides to form thioesters, which are often used as thiol-protecting groups.In the classical reaction, potassium thioacetate replaces the bromine atom to form a thiol in which the thioester formed in the first step is subjected to a nucleophilic addition elimination reaction to obtain a thiol via hydrolysis, alcoholysis or ammonolysis. Unlike the thiol formation from bromine and thiourea, this method is not strictly limited to polystyrenes. It can also be extended to poly(meth)acrylate systems. It is important that there is no observation of ester hydrolysis during the process.