ChemicalBook > CAS DataBase List > 1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
- CAS No.78858-44-3
- Chemical Name:1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
- CBNumber:CB9167276
- Molecular Formula:C25H54NO6P
- Formula Weight:495.68
- MOL File:78858-44-3.mol
1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE Property
- solubility PBS (pH 7.2): 5 mg/ml
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE Chemical Properties,Usage,Production
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Description
2-
O- methyl PAF C- 16 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn- 2 position. Although the biological activities of 2- O- methyl PAF C- 16 have not been well characterized, the C- 18 analog has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart. In rat astrocytes, the C- 18 analog causes the release of large quantities of NO by a pathway involving activation of NOS. - Uses 2-O-Methyl PAF C-16 (ET-18-O-OCH3), a structural analog of the mediator of inflammation platelet-activating factor (PAF), is a cytotoxic ether lipid. 2-O-Methyl PAF C-16 stimulates TNF-α release in murine macrophages[1].
- References [1] R Shames, et al. Tumor necrosis factor release by murine macrophages stimulated by the cytotoxic ether lipid 1-O-hexadecyl-2-O-methyl-SN-glycero-3-phosphorylcholine (ET-18-O-OCH3). Int J Immunopharmacol. 1994 Apr;16(4):335-43. DOI:10.1016/0192-0561(94)90009-4
1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global(22)Suppliers
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78858-44-3, 1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINERelated Search:
- 1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-DIHEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE DIHYDRATE 1,2-DIHEPTADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE 1-OCTADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE phosphorylcholine PAF (C18) 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE POPC 1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE 1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine 1-O-HEXADECYL-2-ARACHIDONYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE 1-O-HEXADECYL-2-N-METHYLCARBAMYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- 抑制剂
- C25H54NO6P
- 化合物 2-O-METHYL PAF C-16
- 78858-44-3
- 1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine
- RZNRKXGAJMGLIM-RUZDIDTESA-N
- 1-hexadecyl-2-methoxyglycero-3-phosphocholine
- 2-O-METHYL PAF C-16
- 1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
