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4-Hydroxycinnamic acid

CAS No.7400-08-0
Chemical Name:4-Hydroxycinnamic acid
CBNumber:CB9164396
Molecular Formula:C9H8O3
Formula Weight:164.16
MOL File:7400-08-0.mol

4-Hydroxycinnamic acid Property

Melting point 214 °C (dec.)(lit.)
Boiling point 251.61°C (rough estimate)
Density 1.2132 (rough estimate)
refractive index 1.5380 (estimate)
storage temp. Store below +30°C.
solubility Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka 4.65±0.10(Predicted)
form Solid
color White to Off-White
biological source rabbit
Stability Light Sensitive
InChI InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)
InChIKey NGSWKAQJJWESNS-UHFFFAOYSA-N
SMILES C(O)(=O)C=CC1=CC=C(O)C=C1
LogP 1.790
CAS DataBase Reference 7400-08-0(CAS DataBase Reference)
FDA UNII IBS9D1EU3J
NIST Chemistry Reference 2-Propenoic acid, 3-(4-hydroxyphenyl)-(7400-08-0)
EPA Substance Registry System p-Hydroxycinnamic acid (7400-08-0)
UNSPSC Code 12352203
NACRES NA.41

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36-36/37/39-22
WGK Germany :2
RTECS :GD9095000
HS Code :2918 29 00

NFPA 704:

	1
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338

4-Hydroxycinnamic acid Price More Price(3)

Brand: Sigma-Aldrich(India)
Product number: 8.00237
Product name : 4-Hydroxycinnamic acid
Purity: for synthesis
Packaging: 10G
Price: ₹5200.01
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: SAB1303797
Product name : ANTI-ACER3 (C-TERM) antibody produced in rabbit
Purity: IgG fraction of antiserum, buffered aqueous solution
Packaging: 400μL
Price: ₹47796.6
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 8.00237
Product name : 4-Hydroxycinnamic acid
Purity: for synthesis
Packaging: 50G
Price: ₹13290.01
Updated: 2022/06/14
Buy: Buy

4-Hydroxycinnamic acid Chemical Properties,Usage,Production

Chemical Properties Light yellow to beige crystalline powder with aroma, soluble in methanol, ethanol, DMSO and other organic solvents, derived from synthesis.
Uses 4-Hydroxycinnamic acid is the hydroxy derivative of Cinnamic Acid with antioxidant properties. It is a is a major component of lignocellulose. Studies suggest that 4-Hydroxycinnamic acid may reduce the risk of cancer by reducing the formation of carcinogenic nitrosamines. A recent study reports that 4-Hydroxycinnamic acid may act as a chemical castrator in bees by altering the epression of genes required for ovary development. This compound is common in pollen a major constituent of the worker bee diet, but it is not found in queen bees'royal jelly.
Application p-Hydroxycinnamic acid is mainly used as an intermediate in the pharmaceutical and perfume industries. It can react with dimethyl sulfate to produce p-anisaldehyde, react with acetaldehyde to produce p-hydroxycinnamaldehyde, and further oxidize it to produce cinnamic acid. This product can be directly oxidized to produce 4-Hydroxybenzoic acid and reduction to produce 4-Hydroxybenzyl alcohol.
Definition ChEBI: 4-coumaric acid is a coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring. It has a role as a plant metabolite. It is a conjugate acid of a 4-coumarate.
Hazard Moderately toxic.
Safety Profile Moderarely toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See also COUMARIN