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QUERCETINPENTAACETATE
QUERCETINPENTAACETATE
- CAS No.1064-06-8
- Chemical Name:QUERCETINPENTAACETATE
- CBNumber:CB91405559
- Molecular Formula:C25H20O12
- Formula Weight:512.42
- MOL File:1064-06-8.mol
QUERCETINPENTAACETATE Property
- Melting point 193 °C
- Boiling point 666.4±55.0 °C(Predicted)
- Density 1.45±0.1 g/cm3(Predicted)
- storage temp. Store at -20°C
- solubility Dichloromethane, Ethyl Acetate
- form Solid
- color Beige
- FDA UNII G0B9KJ0VKI
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
QUERCETINPENTAACETATE Chemical Properties,Usage,Production
- Description Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).
- Uses [5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.
QUERCETINPENTAACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
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1064-06-8, QUERCETINPENTAACETATERelated Search:
- 7-METHOXYFLAVONOL Isorhamnetin 4-ACETOXY-3-METHOXYCINNAMALDEHYDE ARTEMISININ 2'-HYDROXY-4,4',6'-TRIMETHOXYCHALCONE 3',4',7-TRIMETHOXYFLAVONE QUERCETIN-3,7,3',4'-TETRAMETHYL ETHER 2',4-DIHYDROXY-4',6'-DIMETHOXYCHALCONE 2,4,6-Trimethoxybenzaldehyde QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER 3',4',5,7-TETRAMETHOXYFLAVONE 3,4-Diethoxybenzyl alcohol 3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE 5,7-DIMETHOXYFLAVONE KAEMPFEROL-3,7,4'-TRIMETHYL ETHER FLAVONE 7-HYDROXY-5-METHOXY-2-PHENYL-CHROMEN-4-ONE 5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
- 抑制剂
- 五乙酰槲皮素
- 化合物QUERCETIN PENTAACETATE,10 MM DMSO 溶液
- 槲皮素五乙酸酯
- 化合物QUERCETIN PENTAACETATE
- 1064-06-8
- Quercetin pentaacetate, 10 mM in DMSO
- 2-(3,4-diacetoxyphenyl)-4-oxo-4H-chromene-3,5,7-triyl triacetate
- Quercetin pentaacetate,Respiratory syncytial virus,inhibit,Inhibitor,RSV
- 4H-1-Benzopyran-4-one, 3,5,7-tris(acetyloxy)-2-[3,4-bis(acetyloxy)phenyl]-
- [5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate
- Pentaacetylquercetin
- 3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one
- Quercetine pentaacetate
- Quercetin acetate
- 3,3',4',5,7-Pentaacetoxyflavone
- 3,3',4',5,7-Penta(acetyloxy)flavone