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lithospermic acid
lithospermic acid
- CAS No.28831-65-4
- Chemical Name:lithospermic acid
- CBNumber:CB91357544
- Molecular Formula:C27H22O12
- Formula Weight:538.46
- MOL File:28831-65-4.mol
lithospermic acid Property
- Melting point 183-188 °C
- Boiling point 862.6±65.0 °C(Predicted)
- Density 1.642±0.06 g/cm3(Predicted)
- storage temp. under inert gas (nitrogen or Argon) at 2-8°C
- solubility Soluble in methan
- form powder
- pka 2.77±0.10(Predicted)
- color White
- FDA UNII 100IP83JAC
- UNSPSC Code 41116107
- NACRES NA.24
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319
- Precautionary statements P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
lithospermic acid Chemical Properties,Usage,Production
- Uses Shikoric acid has the functions of improving kidney function, preventing and treating cardiovascular diseases, and anti-oxidation.
- Biological Activity Lithospermic acid, a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, has antioxidant and hepatoprotective activities against CCl4-induced acute and in vitro liver injury.
-
in vivo
Lithospermic acid (50 mg/kg, po for 6 days) exhibits cardioprotective efficacy against MI/R injury in mouse models[2].
Lithospermic acid (10-30 mg/kg, po, single dose) exhibits uric acid lowering and anti-inflammatory effects in rats hyperuricemia and gouty arthritis models[3].Animal Model: C57BL/6 mouse MI/R injury models[2] Dosage: 50 mg/kg Administration: po for 6 days Result: Improved MI/R-induced cardiac dysfunction. Animal Model: Hyperuricemia and gouty arthritis model[3] Dosage: 10-30 mg/kg Administration: po, single dose Result: Reduced the serum uric acid and monosodium urate crystal-induced paw edema. - target ROS | ERK | MMP(e.g.TIMP) | DNA/RNA Synthesis | Caspase | TNF-α | HIV | SOD | GPx | Xanthine oxidas | MPO | MDA
lithospermic acid Preparation Products And Raw materials
Raw materials
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28831-65-4, lithospermic acidRelated Search:
- standardized herbal extract
- reference standards from Chinese medicinal herbs (TCM).
- phytochemical
- pharmaceutical intermediate
- chemical reagent
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- 中药对照品
- C27H22O12
- 紫草酸,10 MM DMSO 溶液
- 标准品对照品】LITHOSPERMIC ACID
- 紫精酸
- (2S,3S)-4-((E)-3-((R)-1-羧基-2-(3,4-二羟基苯基)乙氧基)-3-氧代丙烷-1-烯-1-基)-2-(3,4-二羟基苯基)-7-羟基-2,3-二氢苯并呋喃-3-羧酸
- 紫草酸对照品,
- LITHOSPERMIC ACID 紫草酸 标准品
- LITHOSPERMIC ACID 紫草酸
- 紫草酸(标准品)
- 紫草酸
- 28831-65-4
- lithospermic acid, 10 mM in DMSO
- Lithospermic acid-RM
- Alkaloic acid
- Lithospermsaeure
- (2S,3S)-4-[(E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylicaci
- (+)-Lithospermic acid
- (2S,3S)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylic acid
- 3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (2S,3S)-
- (2S,3S)-4-[(E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid
- Clinopodic acid H
- Aids-071478
- Aids071478
- 4-{(E)-2-[1-Carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl}-2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylic acid
- lithospermic acid