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lithospermic acid

lithospermic acid Structure
lithospermic acid
  • CAS No.28831-65-4
  • Chemical Name:lithospermic acid
  • CBNumber:CB91357544
  • Molecular Formula:C27H22O12
  • Formula Weight:538.46
  • MOL File:28831-65-4.mol
lithospermic acid Property
  • Melting point 183-188 °C
  • Boiling point 862.6±65.0 °C(Predicted)
  • Density 1.642±0.06 g/cm3(Predicted)
  • storage temp. under inert gas (nitrogen or Argon) at 2-8°C
  • solubility Soluble in methan
  • form powder
  • pka 2.77±0.10(Predicted)
  • color White
  • FDA UNII 100IP83JAC
  • UNSPSC Code 41116107
  • NACRES NA.24
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319
  • Precautionary statements P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

lithospermic acid Chemical Properties,Usage,Production

  • Uses Shikoric acid has the functions of improving kidney function, preventing and treating cardiovascular diseases, and anti-oxidation.
  • Biological Activity Lithospermic acid, a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, has antioxidant and hepatoprotective activities against CCl4-induced acute and in vitro liver injury.
  • in vivo

    Lithospermic acid (50 mg/kg, po for 6 days) exhibits cardioprotective efficacy against MI/R injury in mouse models[2].
    Lithospermic acid (10-30 mg/kg, po, single dose) exhibits uric acid lowering and anti-inflammatory effects in rats hyperuricemia and gouty arthritis models[3].

    Animal Model:C57BL/6 mouse MI/R injury models[2]
    Dosage:50 mg/kg
    Administration:po for 6 days
    Result:Improved MI/R-induced cardiac dysfunction.
    Animal Model:Hyperuricemia and gouty arthritis model[3]
    Dosage:10-30 mg/kg
    Administration:po, single dose
    Result:Reduced the serum uric acid and monosodium urate crystal-induced paw edema.
  • target ROS | ERK | MMP(e.g.TIMP) | DNA/RNA Synthesis | Caspase | TNF-α | HIV | SOD | GPx | Xanthine oxidas | MPO | MDA
lithospermic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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lithospermic acid Spectrum
28831-65-4, lithospermic acidRelated Search:
  • standardized herbal extract
  • reference standards from Chinese medicinal herbs (TCM).
  • phytochemical
  • pharmaceutical intermediate
  • chemical reagent
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  • C27H22O12
  • 紫草酸,10 MM DMSO 溶液
  • 标准品对照品】LITHOSPERMIC ACID
  • 紫精酸
  • (2S,3S)-4-((E)-3-((R)-1-羧基-2-(3,4-二羟基苯基)乙氧基)-3-氧代丙烷-1-烯-1-基)-2-(3,4-二羟基苯基)-7-羟基-2,3-二氢苯并呋喃-3-羧酸
  • 紫草酸对照品,
  • LITHOSPERMIC ACID 紫草酸 标准品
  • LITHOSPERMIC ACID 紫草酸
  • 紫草酸(标准品)
  • 紫草酸
  • 28831-65-4
  • lithospermic acid, 10 mM in DMSO
  • Lithospermic acid-RM
  • Alkaloic acid
  • Lithospermsaeure
  • (2S,3S)-4-[(E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylicaci
  • (+)-Lithospermic acid
  • (2S,3S)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylic acid
  • 3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (2S,3S)-
  • (2S,3S)-4-[(E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid
  • Clinopodic acid H
  • Aids-071478
  • Aids071478
  • 4-{(E)-2-[1-Carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl}-2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylic acid
  • lithospermic acid