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kievitone

kievitone Structure
kievitone
  • CAS No.40105-60-0
  • Chemical Name:kievitone
  • CBNumber:CB91337250
  • Molecular Formula:C20H20O6
  • Formula Weight:356.37
  • MOL File:40105-60-0.mol
kievitone Property
  • Boiling point 639.6±55.0 °C(Predicted)
  • Density 1.384±0.06 g/cm3(Predicted)
  • pka 7.65±0.40(Predicted)
  • LogP 4.600 (est)
  • FDA UNII 96V5H76C4P
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kievitone Chemical Properties,Usage,Production

  • Uses Kievitone, an isoflavanone, could be isolated from hypocotyls of Phaseolus vulgaris L. infected with Rhizoctonia solani Kühn. Kievitone has antifungal activity and antitumor activity[1][2].
  • Definition ChEBI: Kievitone is a hydroxyisoflavanone that is isoflavanone with hydroxy substituents at positions 5, 7, 2' and 4' and a prenyl group at position 8. It has a role as a phytoalexin, an antineoplastic agent and a metabolite. It is a conjugate acid of a kievitone-7-olate.
  • References [1] Smith DA, et, al. Kievitone: the principal antifungal component of “substance II” isolated from Rhizoctonia-infected bean tissues. 1973 Apr;3(14):179-84.
    [2] Hoffman R. Potent inhibition of breast cancer cell lines by the isoflavonoid kievitone: comparison with genistein. Biochem Biophys Res Commun. 1995 Jun 15;211(2):600-6. DOI:10.1006/bbrc.1995.1855
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40105-60-0, kievitoneRelated Search:
  • Iso-Flavones
  • 40105-60-0
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