ChemicalBook > CAS DataBase List > pivalyloxymethyl butyrate

pivalyloxymethyl butyrate

pivalyloxymethyl butyrate Structure
pivalyloxymethyl butyrate
  • CAS No.122110-53-6
  • Chemical Name:pivalyloxymethyl butyrate
  • CBNumber:CB91321048
  • Molecular Formula:C10H18O4
  • Formula Weight:202.25
  • MOL File:122110-53-6.mol
pivalyloxymethyl butyrate Property
  • Boiling point 249.3±13.0 °C(Predicted)
  • Density 1.008±0.06 g/cm3(Predicted)
  • storage temp. -20°C
  • solubility DMSO: ≥10mg/mL
  • form oil
  • color colorless or slightly yellow
  • EWG's Food Scores 1
  • FDA UNII 55VNK5440P
Safety
  • WGK Germany  :nwg
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H402-H315
  • Precautionary statements P273-P501

pivalyloxymethyl butyrate Chemical Properties,Usage,Production

  • Uses AN-9 is an HDAC inhibitor with antimetastic and antiangiogenic properties. Histone deacetylase inhibitors in cancer therapy. Formaldehyde-releasing prodrugs for localized anticancer chemotherapy.
  • in vivo

    Pivanex (AN9, 200 mg/kg, b.i.d, daily) significantly improves the survival of SMN7 SMA mice. Pivanex (AN9) treatment also marked delays the end stage of disease as defined by the onset of body mass loss[3].

    Animal Model:SMN7 SMA mice (SMN2+/+; SMN7+/+; mSmn?/?)[3].
    Dosage:200 mg/kg.
    Administration:Oral administration, b.i.d, at 09.00 and 17.00 daily.
    Result:Improved the mean lifespan of treated SMN7 SMA mice by 84.6%.
    Delayed the onset of body mass loss in SMN7 SMA mice by 94.9%.
  • IC 50 HDAC; Bcr-Abl
pivalyloxymethyl butyrate Preparation Products And Raw materials
Raw materials
Preparation Products
pivalyloxymethyl butyrate Suppliers
Global(28)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    Aladdin Scientific
  • Tel：
  • Email：tp@aladdinsci.com
  • Country：United States
  • ProdList：57505
  • Advantage：58
  • Supplier： Energy Chemical
  • Tel：021-58432009<br/>400-005-6266
  • Email：marketing1@energy-chemical.com
  • Country：China
  • ProdList：44812
  • Advantage：58
pivalyloxymethyl butyrate Spectrum
122110-53-6, pivalyloxymethyl butyrateRelated Search:
  • 抑制剂
  • 高端化学
  • 医药研发中间体
  • 化合物PIVANEX,10 MM DMSO 溶液
  • 化合物PIVANEX
  • (2,2-二甲基-1-氧代丙氧基)丁酸甲酯
  • 新戊酰基氧基甲基丁酸酯
  • 化合物 T16545
  • 122110-53-6
  • Pivanex, 10 mM in DMSO
  • Chronic,leukemia,AN 9,muscular,Acute,ALL,atrophy,Inhibitor,lung,Histone deacetylases,NSCLC,myelogenous,lymphoblastic,cancer,HDAC,AN9,CML,Pivanex,spinal,K562,Apoptosis,inhibit,Bcr-Abl
  • Pivanex
  • Butanoic acid, (2,2-dimethyl-1-oxopropoxy)methyl ester
  • Brn 4861411
  • ((2,2-Dimethylpropanoyl)oxy)methyl butanoate
  • pivalyloxymethyl butyrate

Home

My