ChemicalBook > CAS DataBase List > 4-(cyclohexylsulfamoyl)benzoic acid
4-(cyclohexylsulfamoyl)benzoic acid
- CAS No.6314-70-1
- Chemical Name:4-(cyclohexylsulfamoyl)benzoic acid
- CBNumber:CB91257767
- Molecular Formula:C13H17NO4S
- Formula Weight:283.34
- MOL File:6314-70-1.mol
4-(cyclohexylsulfamoyl)benzoic acid Property
- Melting point 259-260 °C
- Boiling point 473.4±47.0 °C(Predicted)
- Density 1.36±0.1 g/cm3(Predicted)
- pka 3.54±0.10(Predicted)
- form Solid
- color White to off-white
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
4-(cyclohexylsulfamoyl)benzoic acid Chemical Properties,Usage,Production
- Description NSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM).
- Uses INK4C-IN-2 (Compound 40) is the inhibitor for INK4C (also known as p18) and the activator for CDK4/6. INK4C-IN-2 increases the number and expansion capacity of mouse and human hematopoietic stem cells (HSCs) with EC50 of 5.21 nM, promotes the self-renewal and multilineage differentiation of HSCs. INK4C-IN-2 improves the expansion and long-term hematopoietic reconstruction ability of HSCs in mouse bone marrow transplantation model[1].
- References [1] Xie XQ, et al., Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci Rep. 2015 Dec 18;5:18115. DOI:10.1038/srep18115
4-(cyclohexylsulfamoyl)benzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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6314-70-1, 4-(cyclohexylsulfamoyl)benzoic acidRelated Search:
- 2,4-Thiazolidinedione,5-[(4-hydroxy-3-methoxyphenyl)methylene]- 4-Chloro-N,N-diisopropylbenzamide Pifithrin-μ 2-Pyridinecarbothioamide, N-2-pyridinyl- 1,3-Bis(4-aminophenyl)urea 5-(4-iodobenzylidene)rhodanine S3I-201 NSC228155 NSC632839hydrochloride NSC23005 Sodium HAMNO NSC 247030 5-[(4-chlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione NSC781406 TIMTEC-BB SBB006342 4-Chloro-N,N-di-n-propylbenzaMide, 97% 4-Chloro-N,N-diethylbenzaMide, 97% 5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE
- 抑制剂
- 对照品
- 化合物NSC23005,10 MM DMSO 溶液
- 4-(N-环己基氨磺酰基)苯甲酸
- 4-(环己基氨基磺酰基)苯甲酸
- 化合物NSC23005
- 6314-70-1
- INK4C-IN-2
- NSC23005, 10 mM in DMSO
- Benzoic acid, 4-[(cyclohexylamino)sulfonyl]-
- 4-(N-Cyclohexylsulfamoyl)benzoic acid
- NSC23005 free acid
- NSC23005
