ChemicalBook > CAS DataBase List > BETA-SECRETASE INHIBITOR IV
BETA-SECRETASE INHIBITOR IV
BETA-SECRETASE INHIBITOR IV
- CAS No.797035-11-1
- Chemical Name:BETA-SECRETASE INHIBITOR IV
- CBNumber:CB8835547
- Molecular Formula:C31H38N4O5S
- Formula Weight:578.72
- MOL File:797035-11-1.mol
BETA-SECRETASE INHIBITOR IV Property
- Density 1.30±0.1 g/cm3(Predicted)
- storage temp. Store at -20°C
- solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
- form A crystalline solid
- pka 13.72±0.46(Predicted)
- color Off-white to light yellow
- UNSPSC Code 12352200
- NACRES NA.77
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
BETA-SECRETASE INHIBITOR IV Chemical Properties,Usage,Production
- Uses beta-Secretase Inhibitor IV is a compound that binds to the active site of BACE-1 and potently blocks its proteolytic activity.
-
Biological Activity
Cell permeable: yes', 'Primary Target
β-Secretase', 'Reversible: yes', 'Target IC50: 15 nM for BACE-1, human and 29 nM for sAPP_NF in HEK293-APPNFEV cells
BETA-SECRETASE INHIBITOR IV Preparation Products And Raw materials
Raw materials
Preparation Products
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797035-11-1, BETA-SECRETASE INHIBITOR IVRelated Search:
- DAPM GAMMA-SECRETASE INHIBITOR γ-Secretase Inhibitor XXI DAPT DIBENZAZEPINE ISOPHTHALAMIDE BETA-SECRETASE INHIBITOR IV CHEMBRDG-BB 6596991 N-(3-AMINOMETHYL-PHENYL)-METHANESULFONAMIDE β-Secretase Inhibitor II 1PC x 5MG β-Secretase Activity Assay Kit β-Secretase Inhibitor III 1PC x 500UG β-Secretase Inhibitor IV 1PC x 1MG β-Secretase Inhibitor II 1PC x 1MG β-Secretase Substrate IV, Fl 1PC x 1MG
- Human β-secretase (BACE-1) inhibitor.
- 抑制剂
- C31H38N4O5S
- Β-分泌酶抑制剂IV
- 化合物 Β-SECRETASE INHIBITOR IV
- 化合物 T13434
- BACE-1抑制剂
- 797035-11-1
- γ-Secretase Inhibitor IV
- βSecretase Inhibitor IV,β Secretase Inhibitor IV
- γ-Secretase Inhibitor IV
- 3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
- BACE-1 inhibitor
- N-((1S,2R)-1-BENZYL-3-CYCLOPROPYLAMINO-2-HYDROXY-PROPYL)-5-(METHANESULFONYL-METHYL-AMINO)-N'-((R)-1-PHENYL-ETHYL)-ISOPHTHALAMIDE
- β-Secretase Inhibitor IV
- N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-5-(N-methylmethylsulfonamido)-N3-((R)-1-phenylethyl)isophthalamide
- 1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]-
- BETA-SECRETASE INHIBITOR IV