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BETA-SECRETASE INHIBITOR IV

BETA-SECRETASE INHIBITOR IV Structure
BETA-SECRETASE INHIBITOR IV
  • CAS No.797035-11-1
  • Chemical Name:BETA-SECRETASE INHIBITOR IV
  • CBNumber:CB8835547
  • Molecular Formula:C31H38N4O5S
  • Formula Weight:578.72
  • MOL File:797035-11-1.mol
BETA-SECRETASE INHIBITOR IV Property
  • Density 1.30±0.1 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
  • form A crystalline solid
  • pka 13.72±0.46(Predicted)
  • color Off-white to light yellow
  • UNSPSC Code 12352200
  • NACRES NA.77
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

BETA-SECRETASE INHIBITOR IV Chemical Properties,Usage,Production

  • Uses beta-Secretase Inhibitor IV is a compound that binds to the active site of BACE-1 and potently blocks its proteolytic activity.
  • Biological Activity Cell permeable: yes', 'Primary Target
    β-Secretase', 'Reversible: yes', 'Target IC50: 15 nM for BACE-1, human and 29 nM for sAPP_NF in HEK293-APPNFEV cells
BETA-SECRETASE INHIBITOR IV Preparation Products And Raw materials
Raw materials
Preparation Products
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BETA-SECRETASE INHIBITOR IV Spectrum
797035-11-1, BETA-SECRETASE INHIBITOR IVRelated Search:
  • Human β-secretase (BACE-1) inhibitor.
  • 抑制剂
  • C31H38N4O5S
  • Β-分泌酶抑制剂IV
  • 化合物 Β-SECRETASE INHIBITOR IV
  • 化合物 T13434
  • BACE-1抑制剂
  • 797035-11-1
  • γ-Secretase Inhibitor IV
  • βSecretase Inhibitor IV,β Secretase Inhibitor IV
  • γ-Secretase Inhibitor IV
  • 3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
  • BACE-1 inhibitor
  • N-((1S,2R)-1-BENZYL-3-CYCLOPROPYLAMINO-2-HYDROXY-PROPYL)-5-(METHANESULFONYL-METHYL-AMINO)-N'-((R)-1-PHENYL-ETHYL)-ISOPHTHALAMIDE
  • β-Secretase Inhibitor IV
  • N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-5-(N-methylmethylsulfonamido)-N3-((R)-1-phenylethyl)isophthalamide
  • 1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]-
  • BETA-SECRETASE INHIBITOR IV