Description
Cinitapride is a substituted benzamide dopamine receptor antagonist effective in the
treatment of gastroesophageal reflux and a variety of gastrointestinal motility disorders.
It generates strong procholinergic activity in the gastrointestinal tract by elevating the
serotonergic transmission in the mysenteric plexus.
Chemical Properties
White Solid
Originator
Almirall (Spain)
Uses
serotonin-norepinephrine reuptake inhibitor, antidepressant
Uses
A novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors (1,2,3).
Definition
ChEBI: Cinitapride is an aromatic ether and a C-nitro compound.
