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1-Chloro-3-nitrobenzene

CAS No.121-73-3
Chemical Name:1-Chloro-3-nitrobenzene
CBNumber:CB8747505
Molecular Formula:C6H4ClNO2
Formula Weight:157.55
MOL File:121-73-3.mol

1-Chloro-3-nitrobenzene Property

Melting point 43-47 °C(lit.)
Boiling point 236 °C(lit.)
Density 1.534 g/mL at 25 °C(lit.)
vapor pressure 1.9Pa at 25℃
refractive index 1.5545 (estimate)
Flash point 218 °F
storage temp. Store below +30°C.
solubility alcohol: freely soluble (hot)(lit.)
form powder to lump to clear liquid
color White or Colorless to Yellow
PH 7 (0.26g/l, H2O, 20℃)
Water Solubility INSOLUBLE
Merck 14,2151
BRN 1907947
Stability Stable. Incompatible with strong oxidizing agents, strong acids, strong reducing agents.
LogP 2.49
CAS DataBase Reference 121-73-3(CAS DataBase Reference)
FDA UNII 8XSA3GF8O1
NIST Chemistry Reference Benzene, 1-chloro-3-nitro-(121-73-3)
EPA Substance Registry System m-Chloronitrobenzene (121-73-3)
UNSPSC Code 12352100
NACRES NA.22

Safety

Hazard Codes :Xn,N,T
Risk Statements :22-50/53-23/24/25
Safety Statements :22-24/25-60-61-45-38-36/37/39-28A
RIDADR :UN 1578 6.1/PG 2
WGK Germany :2
RTECS :CZ0940000
Autoignition Temperature :500 °F
TSCA :Yes
HazardClass :6.1
PackingGroup :II
HS Code :29049085
Hazardous Substances Data :121-73-3(Hazardous Substances Data)
Toxicity :mouse,LD50,oral,380mg/kg (380mg/kg),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(8), Pg. 50, 1981.

NFPA 704:

	1
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H302-H311-H412
Precautionary statements P264-P270-P273-P280-P301+P312-P302+P352+P312

1-Chloro-3-nitrobenzene Price More Price(10)

Brand: Sigma-Aldrich(India)
Product number: 218758
Product name : 1-Chloro-3-nitrobenzene
Purity: 98%
Packaging: 250G
Price: ₹4494.3
Updated: 2022/06/14
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Brand: TCI Chemicals (India)
Product number: C0221
Product name : 1-Chloro-3-nitrobenzene
Purity: min. 99.0 %
Packaging: 25G
Price: ₹1500
Updated: 2022/05/26
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Brand: TCI Chemicals (India)
Product number: C0221
Product name : 1-Chloro-3-nitrobenzene
Purity: min. 99.0 %
Packaging: 500G
Price: ₹6100
Updated: 2022/05/26
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Brand: ottokemi
Product number: N 1805
Product name : 3-Nitrochlorobenzene
Purity: 99%
Packaging: 250gm
Price: ₹693
Updated: 2022/05/26
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Brand: ottokemi
Product number: N 1805
Product name : 3-Nitrochlorobenzene
Purity: 99%
Packaging: 500gm
Price: ₹1107
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1-Chloro-3-nitrobenzene Chemical Properties,Usage,Production

Chemical Properties Moist tan or pale yellow crystalline solid
Uses Intermediate for dyes. 1-Chloro-3-nitrobenzene was used in the preparation of aromatic azo compounds using gold (Au) nanoparticles supported on TiO2 as a catalyst. It was also used as surrogate standard to evaluate the removal of 2,4-dinitrotoluene from contaminated soils using enhanced electrokinetic remediation.
Definition ChEBI: 1-chloro-3-nitrobenzene is a C-nitro compound that is nitrobenzene in which one of the meta- hydrogens has been replaced by chlorine. It is a C-nitro compound and a member of monochlorobenzenes.
Production Methods m-Chloronitrobenzene is of lesser economic importance than its ortho- and para-isomers, with no U.S. production reported. The annual production in Germany was reported to be on the order of 1000–3000 metric tons. It has limited use in the manufacturing of dyes and agricultural chemicals.
There is no information on potential exposure. Chloronitrobenzene has been detected in the surface water of the Rhine River with concentrations between 20 and 500 ng/L and in fish at levels of up to 1 mg/kg.
General Description Pale yellow crystals. Insoluble in water.
Air & Water Reactions Insoluble in water.
Reactivity Profile 3-Nitrochlorobenzene can react with oxidizing materials. .
Hazard Toxic by inhalation and ingestion. Combustible. Questionable carcinogen.
Fire Hazard Flash point data for 3-Nitrochlorobenzene are not available. 3-Nitrochlorobenzene is probably combustible.
Flammability and Explosibility Not classified
Safety Profile Poison by ingestion and inhalation. It forms methemoglobin in the body and gves rise to cyanosis and blood changes. Its effects are cumulative and analogous to those of nitrobenzene. The para compound is thought to be somewhat less toxic than the ortho compound. Chemically, it is probably converted in the body to chloroaniline, whch is also poisonous. In industry, it is the dust of hs material that is most often the source of intoxication. Flammable liquid and dangerous fire hazard when exposed to heat or flame. It can react with oxidizing materials. When heated to decomposition it emits toxic fumes of Cl-, NOx, and phosgene. See also other chloronitrobenzene entries and NITRO COMPOUNDS of AROMATIC HYDROCARBONS.
Synthesis 1-Chloro-3-nitrobenzene was synthesised from 4-chloro-2-nitro-benzoic acid by adding copper iodide, triethylamine and dimethyl sulfoxide in the presence of inert gas using the Schlenk technique.
Purification Methods Crystallise the nitrobenzene from MeOH or 95% EtOH (charcoal), then pentane. [Beilstein 5 IV 722.]