ChemicalBook > CAS DataBase List > 2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE
2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE
2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE
- CAS No.41933-33-9
- Chemical Name:2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE
- CBNumber:CB8722418
- Molecular Formula:C11H8Cl2N2O
- Formula Weight:255.1
- MOL File:41933-33-9.mol
2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE Property
- Melting point 86 °C(Solv: hexane (110-54-3))
- Boiling point 338.0±52.0 °C(Predicted)
- Density 1.38±0.1 g/cm3(Predicted)
- storage temp. under inert gas (nitrogen or Argon) at 2-8°C
- pka -3.51±0.20(Predicted)
- form Solid
- color White to off-white
Safety
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H332-H335
- Precautionary statements P280-P305+P351+P338-P310
2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE Chemical Properties,Usage,Production
- Uses EcDsbB-IN-9 (Compound 9) is a potent E. coli DsbB (EcDsbB) inhibitor with an IC50 of 1.7 μM and a Ki of 46 nM[1].
- References [1] Landeta C, et al. Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. Nat Chem Biol. 2015 Apr;11(4):292-8. DOI:10.1038/nchembio.1752
2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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41933-33-9, 2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONERelated Search:
- 4,5-DICHLORO-2-(4-METHYLBENZYL)-2,3-DIHYDROPYRIDAZIN-3-ONE 2-(2-CHLORO-6-FLUOROBENZYL)-4,5-DICHLOROPYRIDAZINE-3-(2H)-ONE AURORA 12480 4,5-DICHLORO-2-(2,6-DICHLOROBENZYL)-2,3-DIHYDROPYRIDAZIN-3-ONE AURORA 12806 4,5-DICHLORO-2-(2-FLUOROBENZYL)PYRIDAZINE-3(2H)-ONE AURORA 12558 4,5-DICHLORO-2-(4-CHLOROBENZYL)-2,3-DIHYDROPYRIDAZIN-3-ONE AURORA 12581 2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE AURORA 12539
- 抑制剂
- 4,5-二氯-2-苄基-3(2H)-哒嗪,10 MM DMSO 溶液
- 2-苄基-4,5-二氯哒嗪-3-酮
- 4,5-二氯-2-苄基-3(2H)-哒嗪
- 2-苄基-4,5-二氯哒嗪-3(2H)-酮
- 41933-33-9
- EcDsbB-IN-9, 10 mM in DMSO
- 3(2H)-Pyridazinone, 4,5-dichloro-2-(phenylmethyl)-
- EcDsbBIN9,EcDsbB IN 9
- EcDsbB-IN-9
- 2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE ISO 9001:2015 REACH
- 4,5-dichloro-2-(phenylmethyl)-3(2H)-Pyridazinone
- 2-benzyl-4,5-dichloro-2,3-dihydropyridazinone
- 2-BENZYL-4,5-DICHLOROPYRIDAZINE-3(2H)-ONE
- 2-BENZYL-4,5-DICHLOROPYRIDAZIN-3(2H)-ONE
- 2-BENZYL-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE
- OTAVA-BB BB0128630032