Uses
2-MeS-ATP (2-Methylthio-ATP) is an analog of adenosine nucleotides and acts as a P2Y purinergic receptor agonist specific for adenosine nucleotide activation. 2-MeS-ATP is also able to inhibit the release of toxic mediators from macrophages stimulated by endotoxin (LPS). 2-MeS-ATP can be used in the study of endotoxin shock and inflammatory diseases[1].
Biological Activity
P2 purinoceptor agonist.
References
[1] Proctor R A, et al. Protection of mice from endotoxic death by 2-methylthio-ATP[J]. Proceedings of the National Academy of Sciences, 1994, 91(13): 6017-6020. DOI:
10.1073/pnas.91.13.6017
