ChemicalBook > CAS DataBase List > BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE

BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE

BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Structure
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
  • CAS No.23749-58-8
  • Chemical Name:BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
  • CBNumber:CB8476272
  • Molecular Formula:C18H10N2O
  • Formula Weight:270.28
  • MOL File:23749-58-8.mol
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Property
  • Melting point 189 °C
  • Boiling point 613.6±38.0 °C(Predicted)
  • Density 1.40±0.1 g/cm3(Predicted)
  • pka 2.05±0.20(Predicted)
  • form powder
  • color Bright yellow
  • EWG's Food Scores 1
Safety
  • HS Code  :2933998090
  • NFPA 704:
    1
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P264-P271-P280-P312

BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Chemical Properties,Usage,Production

  • Uses AHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. AHR agonist 3 inhibits triple-negative breast cancer (TNBC) stem cell growth via AhR while exhibits minimal cytotoxicity against normal human primary cells and can be used for cancer research[1].
  • Properties and Applications

    TEST ITEMS

    SPECIFICATION

    APPEARANCE

    YELLOW POWDER

    SHADE

    GREENISH

    HEAT RESISTANCE

    260 °C min

    LIGHT FASTNESS

    5-6

    ACID RESISTANCE

    5

    ALKALI RESISTANCE

    5

    WATER RESISTANCE

    5

    DENSITY

    1.20 g/cm 3

    RESIDUE ON 80 MESH

    5.0% max

    WATER SOLUBLE

    1.0% max

    VOLATITE 105 °C

    1.0% max

    TINTING STRENGTH

    100-105 %

    WEIGHT METAL TOTAL

    50ppm max

  • References [1] Elson DJ, et.al. Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline. ACS Pharmacol Transl Sci. 2023 Jun 7;6(7):1028-1042. DOI:10.1021/acsptsci.2c00253
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Suppliers
Global(40)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    AFINE CHEMICALS LIMITED
  • Tel：+86-0571-85134551
  • Email：sales@afinechem.com
  • Country：China
  • ProdList：15395
  • Advantage：58
  • Supplier：
    LEAPCHEM CO., LTD.
  • Tel：+86-852-30606658
  • Email：market18@leapchem.com
  • Country：China
  • ProdList：43340
  • Advantage：58
  • Supplier： J & K SCIENTIFIC LTD.
  • Tel： 18210857532
  • Email：jkinfo@jkchemical.com
  • Country：China
  • ProdList：96815
  • Advantage：76
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Spectrum
23749-58-8, BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONERelated Search:
  • C18H10N2O
  • 7H-苯并[DE]苯并[4,5]咪唑并[2,1-A]异喹啉-7-酮
  • 苯并咪唑并[2,1-A]苯并[D,E]异奎千酮-7-酮
  • 7H-苯并咪唑并[2,1-A]苯并[DE]异喹啉-7-酮
  • 23749-58-8
  • AHR agonist 3
  • C.I.Solvent Yellow 184:C.I.71090
  • Fluorescein T
  • 7H-Benzimidazo[2
  • BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
  • 7H-Benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one
  • 7H-7a,12-Diazaindeno[2,1-a]phenalene-7-one
  • 7a,12-Diazaindeno[2,1-a]phenalene-7(7aH)-one
  • 1,8-Naphthoylene-1',2'-benzimidazole
  • Yellow 2GF
  • 7H-Benzimidazo[2,1-a]benz[de]-7-isoquinolinone
  • 7H-Benzimidazol[2,1-a]benz[de]isochinolin-7-on
  • Benzimidazo[2,1-a]benz[d,e]isoquinolion-7-one 98%
  • 1,8-naphthoilene-1,2-benzimidazole (Luminor yellow-green 490 RT)
  • 7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOL
  • Solvent Yellow 184
  • LABOTEST-BB LT00007121
  • yellow-green490rt
  • naphthoylenebenzimidazole
  • luminoryellowgreen490rt
  • luminor2
  • luminophor2
  • 7H-Benzimidazo[2,1-a]benz[d,e]isoquinolin-7-one98%
  • BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE
  • 7H-Benzimidazo[2,1-a]benzo[de]isoquinolin-7-one
  • 7H-Benzimidazo[2,1-a]benz[d,e]isoquinolin-7-one 98%
  • luminogren
  • luminoforyellow-green490rt
  • 7h-benzimidazo(2,1-a)benz(de)isoquinolin-7-one

Home

My