Uses
ChemicalBook > CAS DataBase List > ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER

ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER

Uses
ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Structure
ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER
  • CAS No.21085-72-3
  • Chemical Name:ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER
  • CBNumber:CB8396406
  • Molecular Formula:C13H17BrO9
  • Formula Weight:397.17
  • MOL File:21085-72-3.mol
ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Property
  • Melting point 80-110 °C(lit.)
  • Boiling point 388.6±42.0 °C(Predicted)
  • Density 1.52
  • storage temp. Inert atmosphere,Store in freezer, under -20°C
  • solubility Acetonitrile (Slightly), Chloroform (Slightly, Heated, Sonicated), Dichlorometha
  • form Crystalline Powder or Solid
  • color White to gray
  • optical activity [α]/D 188 to 198 °, c =1% (w/v) in ethyl acetate
  • BRN 96281
  • Stability Moisture and Temperature Sensitive
  • InChIKey BCDVKFMSIQGEHB-CIQUZCHMSA-N
  • CAS DataBase Reference 21085-72-3(CAS DataBase Reference)
  • UNSPSC Code 12352201
  • NACRES NA.25
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :22-24/25
  • WGK Germany  :3
  • F  :3-8-10-21
  • Hazard Note  :Irritant/Store Cold under -20oC
  • HS Code  :29189900
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P271-P280
ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: A8292
  • Product name : Acetobromo-α-D-glucuronic acid methyl ester
  • Purity: ≥93%
  • Packaging: 1G
  • Price: ₹14070
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: A8292
  • Product name : Acetobromo-α-D-glucuronic acid methyl ester
  • Purity: ≥93%
  • Packaging: 5G
  • Price: ₹46020
  • Updated: 2022/06/14
  • Buy: Buy

ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Chemical Properties,Usage,Production

  • Uses

    Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of HMR1098-S-glucuronide methyl ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.
    Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of water-soluble glucuronide derivatives of Camptothecin, which is used for cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy (ADEPT).
    Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of glucuronide prodrug compounds of Janus kinase (JAK) inhibitor tofacitinib, which could be cleaved by β-glucuronidase enzymes such as those produced by the microbiome in the gastrointestinal tract, thereby increasing levels of tofacitinib at the site of gastrointestinal inflammation and limiting the systemic exposure of tofacitinib when treating localized inflammatory diseases.

  • Chemical Properties White Crystalline Solid
  • Uses Antitumor agent
ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Suppliers
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ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Spectrum
21085-72-3, ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTERRelated Search:
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Carbohydrates & Derivatives
  • 13C & 2H Sugars
  • carbohydrate
  • 化学试剂
  • 唾液酸类
  • 常用糖合成中间体
  • 糖苷类中间体
  • 碳水化合物
  • 医药中间体
  • 生化试剂
  • Carbohydrate Synthesis
  • Monosaccharides
  • Specialty Synthesis
  • C13H17BrO9
  • 210857-72-3
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  • 葡萄糖醛酸甲基酯
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  • 乙酰溴-Alpha-D-葡萄糖酮酸甲基酯
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  • 乙酰溴-ALPHA-D-葡萄糖酮酸甲基酯
  • 乙酰溴-Α-葡糖醛酸甲酯
  • A-D-葡萄糖醛酸甲基酯
  • A-D-葡萄糖醛酸甲基酯 1G
  • (2R,3R,5S)-2-溴-6-(甲氧羰基)四氢-2H-吡喃-3,4,5-三基三乙酸酯
  • Α-D -葡萄糖醛酸甲基酯
  • 1-溴-1-脱氧-2,3,4-三-O-乙酰基-ALPHA-D-葡萄糖醛酸甲酯
  • 乙酰溴-ALPHA-D-葡萄糖醛酸甲酯
  • 乙酰溴-Α-D-葡萄糖醛酸甲酯
  • 乙酰溴-Α-D-葡萄糖酮酸甲基酯
  • 21085-72-3
  • Acetobromo-α-<sc>D</sc>-glucuronic acid methyl ester
  • D-Glucuronic Acid-13C6 Sodium Salt Hydrate
  • methyl (2S,3S,4S,5R,6R)-3,4,5-triacetoxy-6-bromo-tetrahydropyran-2-carboxylate
  • α-D-Glucopyranuronic acid, 1-bromo-1-deoxy-, methyl ester, 2,3,4-triacetate
  • Methyl(tri-O-acetyl-α-D-glucopyranosyl bromide)uronate
  • Acetobromo- α-D-glucuronic acid methyl ester
  • Bromo-2,3,4-tri-O-acetyl-α-d-glucopyranuronic Acid Methyl Ester
  • acetobromo-α-d-glucuronic acid methyl ester
  • Methyl acetobromo-α-D-glucuronate
  • (2R,3R,4S,5S,6S)-2-BroMo-6-(Methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
  • METHYL ACETOBROMO-ALPHA-D-GLUCURONATE
  • methyl tri-O-acetyl-1-bromo-1-deoxy-α-D-glucopyranuronate

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