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2-PHENYL-PYRIDIN-4-YLAMINE

2-PHENYL-PYRIDIN-4-YLAMINE Structure
2-PHENYL-PYRIDIN-4-YLAMINE
  • CAS No.21203-86-1
  • Chemical Name:2-PHENYL-PYRIDIN-4-YLAMINE
  • CBNumber:CB8370897
  • Molecular Formula:C11H10N2
  • Formula Weight:170.21
  • MOL File:21203-86-1.mol
2-PHENYL-PYRIDIN-4-YLAMINE Property
  • Boiling point 384.2±30.0 °C(Predicted)
  • Density 1.133±0.06 g/cm3(Predicted)
  • storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
  • pka 8.22±0.10(Predicted)
  • form solid
  • color Pale yellow
Safety
  • Risk Statements  :41
  • Safety Statements  :26-39
  • HS Code  :2933399990
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

2-PHENYL-PYRIDIN-4-YLAMINE Chemical Properties,Usage,Production

  • Uses 2-PPA is a selective inhibitor of TMEM175 (IC50=32 μM) with activity in modulating lysosomal function. Acute inhibition of TMEM175 by 2-PPA increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. 2-PPA can be used in the study of Parkinson's disease[1].
  • References [1] SeCheol, et al. "Discovery of Selective Inhibitors for the Lysosomal Parkinson’s Disease Channel TMEM175." Journal of the American Chemical Society (2024). DOI:10.1021/jacs.4c05623
2-PHENYL-PYRIDIN-4-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-PHENYL-PYRIDIN-4-YLAMINE Suppliers
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2-PHENYL-PYRIDIN-4-YLAMINE Spectrum
21203-86-1, 2-PHENYL-PYRIDIN-4-YLAMINERelated Search:
  • API intermediates
  • 其它
  • 医药中间体
  • 4-氨基-2-苯基吡啶
  • 2-苯基吡啶-4-胺
  • 2-苯基-4-氨基吡啶
  • 21203-86-1
  • 2-PPA
  • 4-Pyridinamine, 2-phenyl-
  • Pyridine, 4-amino-2-phenyl-
  • 2-Phenylpyridin-4-aMine
  • 2-PHENYL-PYRIDIN-4-YLAMINE
  • 4-AMINO-2-PHENYLPYRIDINE

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