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6-HYDROXYFLAVONE

6-HYDROXYFLAVONE Structure
6-HYDROXYFLAVONE
  • CAS No.6665-83-4
  • Chemical Name:6-HYDROXYFLAVONE
  • CBNumber:CB8347347
  • Molecular Formula:C15H10O3
  • Formula Weight:238.24
  • MOL File:6665-83-4.mol
6-HYDROXYFLAVONE Property
  • Melting point 234-236 °C (lit.)
  • Boiling point 320.83°C (rough estimate)
  • Density 1.2653 (rough estimate)
  • refractive index 1.5740 (estimate)
  • pka 8.98±0.40(Predicted)
  • form powder to crystal
  • color Light yellow to Yellow to Green
  • BRN 15827
  • LogP 4.445 (est)
  • CAS DataBase Reference 6665-83-4(CAS DataBase Reference)
  • FDA UNII 148S6Z78H6
  • UNSPSC Code 12352100
  • NACRES NA.22
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :26-37/39
  • WGK Germany  :3
  • Hazard Note  :Irritant
  • HS Code  :2932.99.7000
  • NFPA 704:
    0
    0 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H335-H315-H319
  • Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
6-HYDROXYFLAVONE Price More Price(6)
  • Brand: Sigma-Aldrich(India)
  • Product number: 411035
  • Product name : 6-Hydroxyflavone
  • Purity: 98%
  • Packaging: 1G
  • Price: ₹2695.43
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H0851
  • Product name : 6-Hydroxyflavone
  • Purity: 
  • Packaging: 1G
  • Price: ₹2200
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-B25016-14
  • Product name : 6-Hydroxyflavone, 98%
  • Purity: 
  • Packaging: 25g
  • Price: ₹43282
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H0851
  • Product name : 6-Hydroxyflavone
  • Purity: 
  • Packaging: 5G
  • Price: ₹8200
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-B25016-06
  • Product name : 6-Hydroxyflavone, 98%
  • Purity: 
  • Packaging: 5g
  • Price: ₹8519
  • Updated: 2022/05/26
  • Buy: Buy

6-HYDROXYFLAVONE Chemical Properties,Usage,Production

  • Chemical Properties light yellow crystals
  • Uses anxiolytic
  • Definition ChEBI: 6-Hydroxyflavone is a hydroxyflavonoid.
  • Synthesis Reference(s) Tetrahedron Letters, 27, p. 2751, 1986 DOI: 10.1016/S0040-4039(00)84634-1
  • in vivo

    6-Hydroxyflavone (6-100 mg/kg; Oral administration; Single dose; 45 minutes before test) has anti-anxiety effect in mouse model[4].
    6-Hydroxyflavone (25-50 mg/kg; Intraperitoneal injection; 15 days) shows protective effect in Cisplatin (HY-17394) -induced nephrotoxicity rat model[5].

    Animal Model:Male ICR mice (20-36 g)[4]
    Dosage:6, 12, 25, 50 and 100 mg/kg
    Administration:Oral administration (p.o.); Single dose; 45 minutes before test
    Result:Showed anti-anxiety effects on behavioral tests.
    Animal Model:Cisplatin (HY-17394) treated male Sprague-Dawley rats (200-250 g)[5]
    Dosage:25 and 50 mg/kg
    Administration:Intraperitoneal injection (i.p.); 15 days
    Result:Significantly attenuated the Cisplatin associated detrimental changes in the body weight, and serum levels of creatinine and urea at both 25 mg/kg and 50 mg/kg.
    Preserved the renal histoarchitecture from the toxicological influence of Cisplatin.
    Reduced the Cisplatin-induced lipid peroxidation and corrected the renal antioxidant status.
6-HYDROXYFLAVONE Preparation Products And Raw materials
Raw materials
Preparation Products
6-HYDROXYFLAVONE Suppliers
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6-HYDROXYFLAVONE Spectrum
6665-83-4, 6-HYDROXYFLAVONERelated Search:
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