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Decapeptide-12

Decapeptide-12 Structure
Decapeptide-12
  • CAS No.137665-91-9
  • Chemical Name:Decapeptide-12
  • CBNumber:CB83128840
  • Molecular Formula:C65H90N18O17
  • Formula Weight:1395.52
  • MOL File:137665-91-9.mol
Decapeptide-12 Property
  • Density 1.51±0.1 g/cm3(Predicted)
  • pka 3.07±0.10(Predicted)
  • Sequence H-Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Decapeptide-12 Chemical Properties,Usage,Production

  • Description Decapeptide-12 is an oligopeptide that is made up of just 10 amino acids. This oligopeptide is known for its anti-tyrosinase activity. Tyrosinase is accountable for producing melanin in the skin. Decapeptide 12 connects to tyrosinase and prevents it from catalyzing the oxidation of phenols – the initial step in melanin creation. It’s able to interfere with tyrosinase and lighten skin.
  • Uses Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM). Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM). Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation [1][2][3].
  • References [1] Anan Abu Ubeid, et al. Short-sequence oligopeptides with inhibitory activity against mushroom and human tyrosinase. J Invest Dermatol. 2009 Sep;129(9):2242-9. DOI:10.1038/jid.2009.124
    [2] Akihito Ochiai, et al. New tyrosinase inhibitory decapeptide: Molecular insights into the role of tyrosine residues. J Biosci Bioeng. 2016 Jun;121(6):607-613. DOI:10.1016/j.jbiosc.2015.10.010
    [3] Basil M H, et al. Tyrosinase inhibitors with potent anti-senescence activity in human neonatal keratinocyte progenitors. J Dermatol Surg Res Ther, 2019, 2019: 30-39.
Decapeptide-12 Preparation Products And Raw materials
Raw materials
Preparation Products
Decapeptide-12 Suppliers
Global(137)Suppliers
  • Supplier：
    American HealthyMorph LLC
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  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
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  • Advantage：58
Decapeptide-12 Spectrum
137665-91-9, Decapeptide-12Related Search:
  • 化学试剂
  • 药物肽
  • 化妆品多肽系列
  • 多肽-美容肽
  • 柏锦生物
  • 美白类
  • 目录多肽
  • 美容多肽
  • 化妆品多肽
  • 美白亮肤肽
  • 化妆品肽
  • 多肽
  • C65H90N18O17
  • DECAPEPTIDE-12十肽-12
  • 10肽-12
  • 十肽-12(LUMIXYL)
  • 十肽-12
  • 137665-91-9
  • Decapeptide-12 lumixyl / cosmetic peptide
  • L-Tyrosine, L-tyrosyl-L-arginyl-L-seryl-L-arginyl-L-lysyl-L-tyrosyl-L-seryl-L-seryl-L-tryptophyl-
  • Decapeptide-12 USP/EP/BP
  • H-Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH
  • Decapeptide-12/ Lumixyl
  • Decapeptide-12

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