ChemicalBook > CAS DataBase List > PHENACETIN-ETHOXY-1-13C
PHENACETIN-ETHOXY-1-13C
PHENACETIN-ETHOXY-1-13C
- CAS No.72156-72-0
- Chemical Name:PHENACETIN-ETHOXY-1-13C
- CBNumber:CB8298744
- Molecular Formula:C10H13NO2
- Formula Weight:180.22
- MOL File:72156-72-0.mol
PHENACETIN-ETHOXY-1-13C Property
- Melting point 134-136 °C(lit.)
- form solid
- UNSPSC Code 12352202
Safety
- Hazard Codes :T
- Risk Statements :45-46-20/21/22-22
- Safety Statements :53-22-36/37/39-45
- WGK Germany :3
-
Symbol(GHS)
- Signal wordDanger
- Hazard statements H350-H302
- Precautionary statements P264-P270-P301+P312-P330-P501
PHENACETIN-ETHOXY-1-13C Chemical Properties,Usage,Production
- Uses Phenacetin-13C is the 13C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4].
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References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Chandrasekharan NV, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13926-31. DOI:10.1073/pnas.162468699
[3] Xiao-Meng He, et al. Effects of long-term smoking on the activity and mRNA expression of CYP isozymes in rats. J Thorac Dis. 2015 Oct 7(10): 1725–1731. DOI:10.3978/j.issn.2072-1439.2015.10.07
[4] Na Gao, et al. Inhibition of Baicalin on Metabolism of Phenacetin, a Probe of CYP1A2, in Human Liver Microsomes and in Rats. PLoS One. 2014 9(2): e89752. DOI:10.1371/journal.pone.0089752
PHENACETIN-ETHOXY-1-13C Preparation Products And Raw materials
Raw materials
Preparation Products
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72156-72-0, PHENACETIN-ETHOXY-1-13CRelated Search:
- Stable Isotopes
- BioChemical
- Alphabetical Listings
- CH3CONHC6H4O13CH2CH3
- 非那西丁(乙酰对氨苯乙醚乙氧基)(乙氧基-1-13C,99%)
- 非那西丁(乙酰对氨苯乙醚乙氧基)(ETHOXY-1-13C,99%)
- 非那西丁-乙氧基-1-13C
- 对乙酰乙氧基苯胺-乙氧基-1-13C
- N-(4-乙氧基-1-13C-苯基)乙酰胺
- 非那西汀-乙氧基-1-13C
- 乙酰对氨苯乙醚乙氧基-1-13C
- 72156-72-0
- Acetamide, N-[4-(ethoxy-1-13C)phenyl]-
- Phenacetin-ethoxy-1-<sup>13</sup>C
- Phenacetin-ethoxy-1-13C,N-(4-Ethoxy-1-13C-phenyl)acetamide, p-Acetophenetidide-ethoxy-1-13C
- Phenacetin- oxethyl-1-13C
- N-(4-Ethoxy-1-13C-phenyl)acetamide, p-Acetophenetidide-ethoxy-1-13C
- phenacetin-13c1(ethoxy-1-13c)
- n-(4-ethoxy-1-13c-phenyl)acetamide
- PHENACETIN-ETHOXY-1-13C, 98 ATOM % 13C
- ACETOPHENETIDIN (ETHOXY-1-13C)
- N-[4-ETHOXYPHENYL]ACETAMIDE (ETHOXY-1-13C)
- P-ACETOPHENETIDIDE-ETHOXY-1-13C
- PHENACETIN-ETHOXY-1-13C