ChemicalBook > CAS DataBase List > FGH-10019
FGH-10019
FGH-10019
- CAS No.1046045-61-7
- Chemical Name:FGH-10019
- CBNumber:CB82627883
- Molecular Formula:C18H19N3O2S2
- Formula Weight:373.49
- MOL File:1046045-61-7.mol
FGH-10019 Property
- Boiling point 578.4±60.0 °C(Predicted)
- Density 1.307±0.06 g/cm3(Predicted)
- pka 7.16±0.10(Predicted)
- form Solid
- color Light yellow to khaki
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
FGH-10019 Chemical Properties,Usage,Production
- Uses FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM.
-
in vivo
FGH10019-treated chow is fed at a dose rate calculated to provide about 0.7 mg analog FGH10019 per day, at about 23 mg/kg body weight, to 5-wk-old male ob/ob mice weighing an average of appr 30 g. After 8 wk on the analog 24-treated chow, the mice gain 8-9 % less weight than control mice[1].
- References [1] Kamisuki S, et al. Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins. J Med Chem. 2011 Jul 14;54(13):4923-7. DOI:10.1021/jm200304y
FGH-10019 Preparation Products And Raw materials
Raw materials
Preparation Products
Global(46)Suppliers
-
Supplier:
- Tel:+1-781-999-5354<br/>+1-00000000000
- Email:marketing@targetmol.com
- Country:United States
- ProdList:32159
- Advantage:58
-
Supplier:
- Tel:86-571-88216897,88216896<br/>13588875226
- Email:sales@hzclap.com
- Country:CHINA
- ProdList:6312
- Advantage:58
-
Supplier:
- Tel:+1-708-310-1919<br/>+1-13798911105
- Email:sales@invivochem.cn
- Country:United States
- ProdList:6391
- Advantage:58
-
Supplier:
- Tel:
- Email:support@targetmol.com
- Country:United States
- ProdList:38630
- Advantage:58
-
Supplier:
- Tel:+86-18621343501;<br/>+undefined18621343501
- Email:product@acmec-e.com
- Country:China
- ProdList:33338
- Advantage:58
-
Supplier:
- Tel:
- Email:tp@aladdinsci.com
- Country:United States
- ProdList:52924
- Advantage:58
-
Supplier:
- Tel: +8613817748580
- Email:cooperation@kean-chem.com
- Country:China
- ProdList:40066
- Advantage:58
- Supplier: Haoyuan Chemexpress Co., Ltd.
- Tel:021-58950125
- Email:info@chemexpress.com
- Country:China
- ProdList:7552
- Advantage:61
- Supplier: LETOPHARM LIMITED
- Tel:+86-21-5821 5861
- Email:sales@letopharm.com
- Country:China
- ProdList:2384
- Advantage:58
- Supplier: SPIRO PHARMA
- Tel:
- Email:eric_feng1954@126.com
- Country:China
- ProdList:9248
- Advantage:55
- 抑制剂
- 化合物FGH-10019,10 MM DMSO 溶液
- N-[4-[2-(2-丙基-4-吡啶基)-4-噻唑基]苯基]甲磺酰胺
- 化合物FGH-10019
- 1046045-61-7
- FGH10019, 10 mM in DMSO
- FGH10019,FGH 10019,inhibit,Inhibitor,Fatty Acid Synthase (FASN)
- Methanesulfonamide, N-[4-[2-(2-propyl-4-pyridinyl)-4-thiazolyl]phenyl]-
- FGH10019;FGH-10019;FGH 10019
- N-(4-(2-(2-propylpyridin-4-yl)thiazol-4-yl)phenyl)methanesulfonamide
- FGH-10019