ChemicalBook > CAS DataBase List > 2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE

2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE

2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Structure
2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE
  • CAS No.56583-49-4
  • Chemical Name:2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE
  • CBNumber:CB8221209
  • Molecular Formula:C20H16N2O5S
  • Formula Weight:396.42
  • MOL File:56583-49-4.mol
2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Property
  • storage temp. Desiccate at +4°C
  • solubility Soluble to 15 mM in ethanol with gentle warming and to 80 mM in DMSO
  • form Powder
  • color Brown to reddish brown
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Chemical Properties,Usage,Production

  • Uses PIT is a purinergic P2Y receptor ligand.
  • Biological Activity Purinergic P2Y receptor ligand. Displays irreversible antagonism at P2Y receptors in some smooth muscles but potentiates responses to ATP in other systems (chick brain recombinant P2Y 1 receptor and sympathetic/purinergic nerve stimulation).
  • in vivo

    PIT (10 mg/kg; i.p.; for 5 days) significantly protects both the white matter and the cortical plate lesions against the insult in mice with S-bromo-willardiine injection induced tonic and tonicoclonic seizures[3].

  • IC 50 P2Y1 Receptor: 0.14 μM μM (IC50)
2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Preparation Products And Raw materials
Raw materials
Preparation Products
2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Suppliers
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2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Spectrum
56583-49-4, 2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATERelated Search:
  • 抑制剂
  • 合成有机化合物配体
  • C13H8N2O2C7H8O3S
  • 3-氧代-2-(吡啶-2-基)-3H-吲哚1-氧化物4-甲基苯磺酸盐
  • 化合物 PIT
  • PIT,PURINERGIC P2Y受体配体
  • 56583-49-4
  • 2,2'-pyridylisatogen tosylate
  • PIT
  • 2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE