ChemicalBook > CAS DataBase List > 2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE
2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE
2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE
- CAS No.56583-49-4
- Chemical Name:2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE
- CBNumber:CB8221209
- Molecular Formula:C20H16N2O5S
- Formula Weight:396.42
- MOL File:56583-49-4.mol
2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Property
- storage temp. Desiccate at +4°C
- solubility Soluble to 15 mM in ethanol with gentle warming and to 80 mM in DMSO
- form Powder
- color Brown to reddish brown
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Chemical Properties,Usage,Production
- Uses PIT is a purinergic P2Y receptor ligand.
- Biological Activity Purinergic P2Y receptor ligand. Displays irreversible antagonism at P2Y receptors in some smooth muscles but potentiates responses to ATP in other systems (chick brain recombinant P2Y 1 receptor and sympathetic/purinergic nerve stimulation).
-
in vivo
PIT (10 mg/kg; i.p.; for 5 days) significantly protects both the white matter and the cortical plate lesions against the insult in mice with S-bromo-willardiine injection induced tonic and tonicoclonic seizures[3].
- IC 50 P2Y1 Receptor: 0.14 μM μM (IC50)
2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Preparation Products And Raw materials
Raw materials
Preparation Products
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56583-49-4, 2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATERelated Search:
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- 56583-49-4
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- 2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE