ChemicalBook > CAS DataBase List > 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Structure
4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
  • CAS No.114772-55-3
  • Chemical Name:4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
  • CBNumber:CB82103743
  • Molecular Formula:C22H22ClN3O
  • Formula Weight:379.88
  • MOL File:114772-55-3.mol
4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Property
  • Melting point 157-158°C
  • Boiling point 605.6±55.0 °C(Predicted)
  • Density 1.19
  • storage temp. Refrigerator
  • solubility DMSO (Slightly), Ethyl Acetate (Slightly)
  • pka 13.66±0.10(Predicted)
  • form Solid
  • color White to Off-White
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Chemical Properties,Usage,Production

  • Uses Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan is a derivative of Losartan Potassium (L470500), a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients.
4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Spectrum
  • Losartan Potassium
  • 化工原料及中间体
  • 原料药
  • 有机化工
  • 医药原料
  • 氯沙坦烃化物/4'-[(2-丁基-4-氯-5-羟甲基-1H-咪唑-1-基)甲基]-1,1'-联苯-2-甲腈
  • 2-丁基-4-氯-1-[(2'-氰基苯-4-基)甲基]-5-羟甲基咪唑
  • 洛沙坦杂质15
  • 2-正丁基-4-氯-1-[(2'-氰基联苯-4-基)-甲基]-5-(羟甲基)咪唑
  • 1'-联苯-2-甲腈
  • 4'-[(2-丁基-4-氯-5-羟甲基-1H-咪唑-1-基)甲基]-1
  • 氯沙坦相关化合物B
  • 氯沙坦杂质8
  • 氯沙坦钾中间体
  • 咪唑缩合物/4'-[(2-丁基-4-氯-5-羟甲基-1H-咪唑-1-基)甲基]-1,1'-联苯-2-甲腈
  • 氯沙坦烃化物(氯沙坦钾中间体)
  • 4'-[(2-丁基-4-氯-5-羟甲基-1H-咪唑-1-基)甲基]-1,1'-联苯-2-甲腈
  • 114772-55-3
  • 2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)-methyl]-5-(hydroxymethyl)imidazole
  • 4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile
  • 4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-
  • Losartan Related Compound B 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1- yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
  • Benzene,1,3,5-tribromo-2,4,10-trimethyl-
  • 2-(4-{[2-Butyl-4-chloro-5-(hydroxymethyl)imidazolyl]methyl} phenyl)benzene carbonitrile
  • Losartan Impurity 8
  • 1'-Biphenyl]-2-carbonitrile
  • 4'-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1
  • 4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile
  • [1,1'-Biphenyl]-2-carbonitrile, 4'-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]-
  • 4'-[(2-BUTYL-4-CHLORO-5-HYDROXYMETHYL-1H-IMIDAZOL-1-YL)METHYL]-1,1'-BIPHENYL-2-CARBONITRILE 114772-55-3
  • 2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile
  • Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan
  • 4′-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)- biphenyl-2-carbonitrile
  • 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile