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6-HYDROXY-2-NAPHTHYL DISULFIDE
6-HYDROXY-2-NAPHTHYL DISULFIDE
- CAS No.6088-51-3
- Chemical Name:6-HYDROXY-2-NAPHTHYL DISULFIDE
- CBNumber:CB8198578
- Molecular Formula:C20H14O2S2
- Formula Weight:350.45
- MOL File:6088-51-3.mol
6-HYDROXY-2-NAPHTHYL DISULFIDE Property
- Melting point 226 °C
- Boiling point 597.5±25.0 °C(Predicted)
- Density 1.46±0.1 g/cm3(Predicted)
- storage temp. −20°C
- solubility <26.28mg/ml in DMSO
- form powder to crystal
- pka 8.93±0.40(Predicted)
- color White to Brown
- Merck 14,2840
- CAS DataBase Reference 6088-51-3(CAS DataBase Reference)
- FDA UNII Y4YW3C2D2S
- Proposition 65 List DDD (Dichlorodiphenyldichloroethane)
- EPA Substance Registry System 2-Naphthalenol, 6,6'-dithiobis- (6088-51-3)
Safety
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319
- Precautionary statements P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
6-HYDROXY-2-NAPHTHYL DISULFIDE Price
More Price(1)
- Brand: TCI Chemicals (India)
- Product number: D0244
- Product name : Bis(6-hydroxy-2-naphthyl) Disulfide
- Purity:
- Packaging: 1G
- Price: ₹6700
- Updated: 2022/05/26
- Buy: Buy
6-HYDROXY-2-NAPHTHYL DISULFIDE Chemical Properties,Usage,Production
- Description DDD, 1,1-dichloro-2,2-bis-(4-chlorophenyl) ethane, also known as TDE, is a metabolite of DDT, which found use in agriculture. As with DDT, the p,p -isomer is insecticidal and the o,p -isomer is an impurity.
- Uses For determination of protein-bound sulfhydryl groups.
- IC 50 PAK1
- Purification Methods It crystallises as leaflets from AcOH and is slightly soluble in EtOH, and AcOH, but is soluble in *C6H6 and in alkalis to give a yellow solution. [Zincke & Dereser Chem Ber 51 352 1918.] The acetoxy derivative has m 198-200o (from AcOH or dioxane/MeOH), and the diacetyl derivative has m 167-168o (from AcOH). A small amount of impure disulfide can be purified by dissolving it in a small volume of Me2CO and adding a large volume of toluene, filter rapidly and concentrate to one-third of its volume. The hot toluene solution is filtered rapidly from any tarry residue, and crystals separate on cooling. Recrystallisation from hot acetic acid gives crystals with m 220-223o [Barrett & Seligman Science 116 323 1952]. [Beilstein 6 I 481.]
-
Toxicity evaluation
Animal Studies. DDD is less acutely toxic
than DDT (29), with an oral LD50 of 3400 to 4000 mg/kg in
the rat and a dermal LD50 ca. 1200 mg/kg in the rabbit. In a
2-year chronic dietary study in the rat, a LOEL of 100 ppm
(5 mg/kg/day) was quoted for tissue damage, similar to that
produced by DDT.
Human Studies. Most of the studies conducted in humans have used the o,p -isomer of DDD. This has been used as a drug, with medical and veterinary uses, for the treatment of Cushing’s syndrome and adrenal carcinoma, under the generic name of mitotane. After oral ingestion, o,p’-DDD binds to lung and adrenal tissue. Its toxicity to the adrenal appears to be species-dependent, however, causing gross atrophy in the dog and reducing corticosteroid production without pathological effects in other mammals, including humans.
6-HYDROXY-2-NAPHTHYL DISULFIDE Preparation Products And Raw materials
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6088-51-3, 6-HYDROXY-2-NAPHTHYL DISULFIDERelated Search:
- Synthetic Organic Chemistry
- Sulfur Compounds (for Synthesis)
- 抑制剂
- 高端化学
- 生化试剂
- 生化试剂-其他化学试剂
- 其他含硫化合物
- Fluorescent Probes, Labels, Particles and Stains
- Detection
- Sulfur Compounds (for Synthesis)
- Biochemicals and Reagents
- BioChemical
- C20H14O2S2
- HOC10H6S2
- 双(6-羟基-2-萘)二硫*5
- 双(6-羟基-2-萘基)二硫化物
- 2,2-二羟基二硫代-6,6-联萘
- 6-羟基-2-萘基二硫醚
- 6,6′-二羟基-2,2′-二萘二硫
- 6,6'-二硫-2,2'-二萘酚 DDD
- 2,2-二羟基二硫代-6,6-联萘 双(6-羟基-2-萘)二硫
- -二萘酚
- -二硫-2,2&APOS
- 6,6'-二硫-2,2'-二萘酚
- 1,1-二氯-2,2-双(4-氯苯基)乙烷
- 2,2ˊ-二羟基-6,6ˊ-二萘二硫
- 双(6-羟基-2-萘)二硫
- 6088-51-3
- 6-[(6-hydroxy-2-naphthalenyl)disulfanyl]-2-naphthalenol
- 6,6'-Disulfanediylbis(naphthalen-2-ol)
- Bis(6-hydroxy-2-naphthyl) Disulfide >
- 6′-Dithiodi(2-naphthol)
- DDD0
- Bis(6-hydroxy-2-naphtyl) persulfide
- 6,6'-Dithiobis(2-naphthol)
- [6,6'-Dithiodinaphthalene]-2,2'-diol
- 2,2μ-Dihydroxy-6,6μ-dinaphthyl disulfide, 6,6μ-Dihydroxy-2,2μ-dinaphthyl disulfide, 6,6μ-Dithiodi(2-naphthol), 6,6μ-Dithiodi-2-naphthol, Bis(2-hydroxy-6-naphthyl) disulfide, Bis(6-hydroxy-2-naphthyl) disulfide, DDD
- 6,6μ-Dihydroxy-2,2μ-dinaphthyl disulfide, 6-Hydroxy-2-naphthyl disulfide, Bis(6-hydroxy-2-naphthyl) disulfide
- 6-HYDROXY-2-NAPHTHYL DISULFIDE 98+%
- 6-HYDROXY-2-NAPHTHYLDISULPHIDE
- 6-HYDROXY-2-NAPHTHYL DISULFIDE 98%
- AKOS BBS-00001974
- 6-HYDROXY-2-NAPHTHYL DISULFIDE
- 6,6'-DIHYDROXY-2,2'-DINAPHTHYL DISULFIDE
- 6,6'-DITHIODI(2-NAPHTHOL)
- 2,2'-DIHYDROXY-6,6'-DINAPHTHYLDISULPHIDE
- 2,2'-DIHYDROXY-6,6'-DINAPHTHYL DISULFIDE
- DDD
- BIS(6-HYDROXY-2-NAPHTHYL) DISULFIDE
- 6,6’-dithiobis-2-naphthaleno
- TIMTEC-BB SBB005947
- Bis(2-hydroxy-6-naphthyl) disulfide
- 6,6&apos
- 2-Naphthalenol,6,6'-dithiobis-
- DDD 6,6'-Dihydroxy-2,2'-dinaphthyl Disulfide 6-Hydroxy-2-naphthyl Disulfide
- DDD (Analytical)
- PIR 3.5
- 6,6'-Dithiodi-2-naphthtol