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FOSALVUDINE TIDOXIL

FOSALVUDINE TIDOXIL Structure
FOSALVUDINE TIDOXIL
  • CAS No.763903-67-9
  • Chemical Name:FOSALVUDINE TIDOXIL
  • CBNumber:CB81509115
  • Molecular Formula:C35H64FN2O8PS
  • Formula Weight:722.93
  • MOL File:763903-67-9.mol
FOSALVUDINE TIDOXIL Property
  • Density 1.14±0.1 g/cm3(Predicted)
  • pka 1.36±0.50(Predicted)
  • FDA UNII TR856337M2
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

FOSALVUDINE TIDOXIL Chemical Properties,Usage,Production

  • Uses Fosalvudine tidoxil is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Fosalvudine tidoxil is a prodrug derived from Alovudine (HY-B1516). Fosalvudine tidoxil is less toxic than Alovudine and can be used for the research of HIV-1 infection[1].
  • in vivo

    Fosalvudine tidoxil (15-100 mg/kg/day; oral; 8 weeks) induces significant mitochondrial hepatotoxicity in rats[1].

    Animal Model:Sprague-Dawley rats[1]
    Dosage:15, 40, or 100 mg/kg/day
    Administration:Oral gavage, 8 weeks
    Result:Induced significant mtDNA depletion. At doses of 15, 40, and 100 mg/kg, the mean hepatic mtDNA values were 62, 64, and 47% of control values, respectively.
  • References [1] Venhoff AC, et al. Mitochondrial DNA depletion in rat liver induced by fosalvudine tidoxil, a novel nucleoside reverse transcriptase inhibitor prodrug. Antimicrob Agents Chemother. 2009 Jul;53(7):2748-51. DOI:10.1128/AAC.00364-09
FOSALVUDINE TIDOXIL Preparation Products And Raw materials
Raw materials
Preparation Products
FOSALVUDINE TIDOXIL Suppliers
Global(4)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
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  • Supplier：
    TargetMol Chemicals Inc.
  • Tel： +8613564774135
  • Email：zijue.cai@tsbiochem.com
  • Country：United States
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  • Supplier： LGM Pharma
  • Tel：1-(800)-881-8210
  • Email：inquiries@lgmpharma.com
  • Country：United States
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  • Supplier： TargetMol Chemicals Inc.
  • Tel： 15002134094
  • Email：marketing@targetmol.cn
  • Country：China
  • ProdList：19727
  • Advantage：58
FOSALVUDINE TIDOXIL Spectrum
763903-67-9, FOSALVUDINE TIDOXILRelated Search:
  • 抑制剂
  • 化合物 FOSALVUDINE TIDOXIL
  • 化合物 T27348
  • 763903-67-9
  • 5'-Thymidylic acid, 3'-deoxy-3'-fluoro-, mono[2-(decyloxy)-3-(dodecylthio)propyl] ester
  • HDP-990003
  • HDP990003
  • HDP-99.0003
  • HDP99.0003
  • HDP 990003
  • HDP 99.0003
  • JHXLLEDIXXOJQD-WELGVCPWSA-N
  • FOSALVUDINE TIDOXIL

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