ChemicalBook > CAS DataBase List > buddlejasaponin IV
buddlejasaponin IV
buddlejasaponin IV
- CAS No.139523-30-1
- Chemical Name:buddlejasaponin IV
- CBNumber:CB81331574
- Molecular Formula:C48H78O18
- Formula Weight:943.12
- MOL File:139523-30-1.mol
buddlejasaponin IV Property
- Melting point 288-290℃
- Density 1.43±0.1 g/cm3 (20 ºC 760 Torr)
- solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form powder
- color White
- FDA UNII HZ7J643R5F
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
buddlejasaponin IV Chemical Properties,Usage,Production
- Uses Buddlejasaponin IV (BS‐IV) exerts anti-inflammatory and cytotoxic effects against cancer cells[1].
- target P21 | Chk | Akt | PARP | Caspase | Bcl-2/Bax | p53 | NOS | COX | IL Receptor | TNF-α | NF-kB | MAPK
-
References
[1] Young Sun Hwang, et al. Buddlejasaponin IV induces cell cycle arrest at G2/M phase and apoptosis in immortalized human oral keratinocytes. Phytother Res. 2011 Oct;25(10):1503-10. DOI:10.1002/ptr.3406
[2] Jong-Heon Won, et al. Anti-inflammatory effect of buddlejasaponin IV through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-kappaB inactivation. Br J Pharmacol. 2006 May;148(2):216-25. DOI:10.1038/sj.bjp.0706718
buddlejasaponin IV Preparation Products And Raw materials
Raw materials
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