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SERGLIFLOZIN

SERGLIFLOZIN Structure
SERGLIFLOZIN
  • CAS No.408504-26-7
  • Chemical Name:SERGLIFLOZIN
  • CBNumber:CB81011753
  • Molecular Formula:C23H28O9
  • Formula Weight:448.46
  • MOL File:408504-26-7.mol
SERGLIFLOZIN Property
  • Boiling point 611.5±55.0 °C(Predicted)
  • Density 1.312
  • pka 12.74±0.70(Predicted)
  • form Solid
  • color White to off-white
  • FDA UNII 4HY3523466
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

SERGLIFLOZIN Chemical Properties,Usage,Production

  • Uses Treatment of type 2 diabetes.
  • Definition ChEBI: Sergliflozin etabonate is a glycoside.
  • in vivo

    Sergliflozin etabonate (1, 3, 10, 30 mg/kg; oral; once) significantly reduces non-fasting blood glucose levels in KK-Ay mice in a dose-dependent manner[1].
    Sergliflozin etabonate (1.7, 8.4, 45.7 mg/kg in the 0.001, 0.005, and 0.025% sergliflozin etabonate; fed; daily for 9 weeks) reduces non-fasting blood glucose level and decreases triglyceride content in the liver in a dose-dependent manner in KK-Ay mice[1].

    Animal Model:14 weeks, Female KK-Ay mice[1]
    Dosage:1, 3, 10, 30 mg/kg
    Administration:Oral; once
    Result:Significantly reduced non-fasting blood glucose level with the reduction in blood glucose level at 2 h post dosing in the 1 mg/kg group, 3 mg/kg group, 10 mg/kg group, and 30 mg/kg group was 12, 15, 28, and 39%, respectively.
    Animal Model:4 weeks, Female KK-Ay mice[1]
    Dosage:1.7, 8.4, 45.7 mg/kg in the 0.001, 0.005, and 0.025% sergliflozin etabonate
    Administration:Fed, daily for 9 weeks
    Result:Reduced non-fasting blood glucose level and decreased triglyceride content in the liver in a dose-dependent manner in diabetic control KK-Ay mice.
  • IC 50 SGLT2
SERGLIFLOZIN Preparation Products And Raw materials
Raw materials
Preparation Products
SERGLIFLOZIN Suppliers
Global(25)Suppliers
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    BOC Sciences
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SERGLIFLOZIN Spectrum
408504-26-7, SERGLIFLOZINRelated Search:
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  • 408504-26-7
  • Sergliflozin etabonate, 10 mM in DMSO
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  • β-D-Glucopyranoside,2-[(4-methoxyphenyl)methyl]phenyl,6-(ethyl carbonate)
  • ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[(4-methoxyphenyl)methyl]phenoxy]oxan-2-yl]methyl carbonate
  • 2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
  • QLXKHBNJTPICNF-QMCAAQAGSA-N
  • Sergliflozin etabonate
  • 2-[(4-Methoxyphenyl)methyl]phenyl-beta-D-glucopyranoside-6-(ethyl carbonate)
  • SERGLIFLOZIN

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