ChemicalBook CAS DataBase List 408504-26-7

408504-26-7

Name	SERGLIFLOZIN
CAS	408504-26-7
Molecular Formula	C23H28O9
MDL Number	MFCD13182360
Molecular Weight	448.46
MOL File	408504-26-7.mol

Chemical Properties

Boiling point	611.5±55.0 °C(Predicted)
density	1.312
form	Solid
pka	12.74±0.70(Predicted)
color	White to off-white

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Shanghai Boyle Chemical Co., Ltd.

Telephone 021-50182298 021-50180596

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ZHIWE CHEMTECH CO LTD

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Chembest Research Laboratories Limited

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Nanjing Chemlin Chemical Co., Ltd

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Beijing Yisiyan Technology Research Center

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AN PharmaTech Co Ltd

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Shanghai YuanYe Biotechnology Co., Ltd.

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Chemleader Biomedical Co., Limited.

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CONIER CHEM AND PHARMA LIMITED

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TargetMol Chemicals Inc.

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Suzhou Meishi Biotechnology Co., Ltd.

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Shanghai Yifei Biotechnology Co. , Ltd.

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Shanghai Aladdin Biochemical Technology Co.,Ltd.

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Shanghai Amole Biotechnology Co., Ltd.

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Shandong Ziyi Pharmaceutical Co., Ltd.

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ATK CHEMICAL COMPANY LIMITED

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DAYANG CHEM (HANGZHOU) CO.,LTD

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Websitewww.dycnchem.com

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Animal Model:	14 weeks, Female KK-Ay mice^[1]
Dosage:	1, 3, 10, 30 mg/kg
Administration:	Oral; once
Result:	Significantly reduced non-fasting blood glucose level with the reduction in blood glucose level at 2 h post dosing in the 1 mg/kg group, 3 mg/kg group, 10 mg/kg group, and 30 mg/kg group was 12, 15, 28, and 39%, respectively.

Animal Model:	4 weeks, Female KK-Ay mice^[1]
Dosage:	1.7, 8.4, 45.7 mg/kg in the 0.001, 0.005, and 0.025% sergliflozin etabonate
Administration:	Fed, daily for 9 weeks
Result:	Reduced non-fasting blood glucose level and decreased triglyceride content in the liver in a dose-dependent manner in diabetic control KK-Ay mice.

408504-26-7

Chemical Properties

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Definition

in vivo

IC 50

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